Acute disseminated encephalomyelitis (ADEM) is a white matter inflammatory disease which usually follows a viral infection or pharmaceutical intervention. We describe a case of presumed ADEM in a heart/lung transplant patient, the etiology of which cannot be elucidated. The fascinating aspect is the mode of clinical presentation and the rapid resolution of radiologic abnormalities. Histologic examination of the brain is provided in an attempt to elucidate the radiographic abnormalities.

Acute disseminated encephalomyelitis (ADEM) is a white matter inflammatory disease which usually follows a viral infection or pharmaceutical intervention. We describe a case of presumed ADEM in a heart/lung transplant patient, the etiology of which cannot be elucidated. The fascinating aspect is the mode of clinical presentation and the rapid resolution of radiologic abnormalities. Histologic examination of the brain is provided in an attempt to elucidate the radiographic abnormalities.

As designers become more aggressive in introducing optical components to micro-systems, rigorous optical models are required for system-level simulation tools. Common optical modeling techniques and approximations are not valid for most optical micro-systems, and those techniques that provide accurate simulation are computationally slow. In this paper, we introduce an angular frequency optical propagation technique that greatly reduces computation time while achieving the accuracy of a full scalar formulation. We present simulations of a diffractive optical MEM Grating Light Valve to show the advantages of this optical propagation method and the integration of the technique into a system-level multi-domain CAD tool.

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