La granulomatosis eosinofílica con poliangeítis, anteriormente conocida como síndrome de Churg-Strauss, es una patología poco frecuente que pertenece al grupo de enfermedades caracterizadas por vasculitis necrotizante de vasos sanguíneos sistémicos de pequeño y mediano calibre. La afectación cardiovascular sintomática ocurre entre un 27% a un 47% de los casos de Churg-Strauss, siendo una de las manifestaciones más graves. El diagnóstico suele confirmarse con biopsia de tejido con infiltración de eosinófilos, pero con la reciente inclusión de la resonancia cardíaca, podemos prescindir de ella.
El diagnóstico precoz es importante debido a que el tratamiento oportuno suele asociarse con mejoría del cuadro.
A total of 200 patients were included. The average daytime ABPM systolic blood pressure (SBP) was 136±16 compared with 136±15 (P=1) with HBPM; the average diurnal diastolic blood pressure (DBP) was 83±12 and 81±9, respectively (P=0.06). The concordance between both methods was very good for SBP [r=0.85; Bland-Altman 0.2 (95% confidence interval 0.9-1.4 mmHg)], and good for the DBP [r=0.77; Bland-Altman 1.8 (95% confidence interval 0.8-2.8 mmHg)]. Both methods were in agreement that HTN was controlled in 68 patients and that it was not controlled in 90 patients, that is, they were concordant in 158 patients (79%, κ=0.6). More patients required changes with ABPM than HBPM (149 vs. 99 patients, P<0.0001) CONCLUSION: There were no significant differences in the measurement of diurnal SBP and DBP between both methods. The concordance to determine proper control of HTN was 79%. There was a significant difference in the decision to modify the treatment in favor of the ABPM.
Eosinophilic granulomatosis with polyangiitis (EGPA), formerly known as Churg-Strauss syndrome, is a rare pathology that belongs to a group of diseases characterized by necrotizing vasculitis of small and medium-sized systemic blood vessels. Symptomatic cardiovascular involvement occurs in 27%–47% of cases of EGPA and is one of the most severe manifestations. The diagnosis is usually confirmed by eosinophilic infiltration observed in tissue biopsy, but with the recent inclusion of cardiac magnetic resonance imaging (MRI), the former can be replaced. Early diagnosis is important because timely treatment is often associated with improvement.
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