Most lymphomas of gastrointestinal tract arise mainly in stomach but can affect small bowel. Burkitt’s lymphoma stands for 9% of the cases of primary small intestine lymphoma and clinical presentations may vary. Case report of a 58-years old man presenting an acute abdomen secondary to intestinal obstruction with tomography revealing an ileocecal mass suspicious for intussusception. Surgery was performed and an invaginating mass from ileum-to-cecum lead to a laparoscopic right colectomy. Histopathological analysis established the diagnosis of ileocecal Burkitt’s lymphoma. Post-operative period was uneventful and the patient was referred to oncohematology and started early chemotherapy. Clinical situations of intestinal intussusception or small-bowel masses presenting with obstruction should rise the suspicion for malignancy and the surgeon must be aware of this clinical entity to proceed with an oncologically safe surgery. Intestinal perforation may indicates surgery as it leads to peritoneal tumor spread and indicates a worse prognosis. Laparoscopic surgery approaches must be seriously considered in selected cases. In intestinal lymphoma, early refer to oncohematology for evaluation and treatment is essential and establishes a better prognosis.

Thyroid metastasization is a very rare phenomenon with a challenging diagnosis. The incidence is 0.36% in all thyroid malignancies and it is reported it would be up to 2% after surgical specimens’ diagnosis. Thyroid metastasization of a malignant melanoma stands with an incidence of 2% in all thyroid secondarism. We report a 41-years old female with cutaneous malignant melanoma resected four years before the start of compressive symptoms secondary to multinodular goiter. Fine-needle-aspiration showed malignant cells of uncertain origin. A total thyroidectomy was performed. Histopathological examination showed multinodular metastases of malignant melanoma. Thyroid metastasis typically presents as a unifocal thyroid mass or nodule and may occur in the absence of a primary tumor diagnosis, thus leading to a misdiagnosis of thyroid primary tumor. Immunostaining and molecular testing are useful in case of doubt. Although metastases generally indicate disseminated disease, some patients may benefit from aggressive thyroid resection surgery when compared to conservative approaches. Newly-diagnosed thyroid mass in any patient with history of malignancy should raise suspicion for metastasizing. Although the overall prognosis of thyroid metastasis is poor, surgery could be an option in some cases with survival improvement or a palliative role.

Myofibroblastoma of the breast is a benign tumor originated from mesenquimal cells with a very low incidence in breast pathology. Only 80 cases were reported until 2018. Eight histological patterns were described and may mimic a number of other breast diseases. A 55-years old male was diagnosed with an incidental left breast nodule. An ultrasonography with biopsy showed a 27 mm nodule compatible with myofibroblastoma. We performed a lumpectomy via modified Benelli technique. Surgery was curative and the only necessary treatment. Myofibroblastoma could be misdiagnosed and clinical differential diagnosis includes other benign and malignant breast lesions. In the setting of a diagnosis, histology may be confusing as myofibroblastoma may exhibit a wide spectrum of histological features that defines 8 variants. These subgroups can mimic malignant lesions in their histological pattern. Definitive diagnosis depends on histopathological and immunochemical results. Physicians must be aware about heterogeneity in morphological and immunochemical aspects of myofibroblastoma and his variants, as they can lead to erroneous management of the lesion. Surgery is important for a definitive and accurate diagnosis, excluding malignancy and relieving the burden of a close image-based surveillance.