The cryopreservation of PBPC components at standard concentrations and 3.3 (1.8-6.2)-fold cell concentrations has no adverse effect on the function of HPCs after thawing.

An especially vulnerable population to traumatic loss, violence exposure, and posttraumatic stress symptoms are those involved in the juvenile justice system. However, justice-involved youth are not a homogeneous group. Research looking at subpopulations within juvenile justice systems highlight the diverse backgrounds and treatment needs of justice-involved youth such as those who are also gang-involved. The current study seeks to address the interrelated issues of behavioral health, traumatic grief, loss, and self-reported turning points among a sample of formerly incarcerated youth who report extensive juvenile justice histories ( N = 62). All youth participated in an extensive survey interview. Just over half (56.5%) of the youth reported being gang-involved. Chi-square analyses revealed that gang- and justice-involved youth were significantly more likely to have experienced traumatic loss compared with their justice-only peers (χ2 = 4.265, p < .05). Gang involvement approximately doubled youth’s exposure to community violence, both direct and witnessed, and there were significant differences in the levels of posttraumatic stress symptoms and substance use, between the gang- and justice-involved youth compared with the justice-only youth. When asked to describe a turning point in their lives, 15% of the sample described significant loss and how it affected their lives, for better or worse. Findings lend support for a focus on supporting posttraumatic growth and increasing access to trauma-focused treatment, with an emphasis on grief and loss, for those who are both gang- and justice-involved.

Gang research has spanned nearly a century. In that time, we have learned that gang membership increases the chances of involvement in homicide as a victim or offender. The violence that embroils gang life, both instrumental and symbolic, often has consequences. In this paper we review the gang homicide literature covering topics such as definitional issues, available data, correlates and characteristics, and theoretical explanations. The review examines individual, group, and structural contexts for gang homicide. We conclude with a discussion of future needs in theory, data, and methods, to improve our understanding of gang homicide.

Community violence intervention and prevention initiatives aim to develop local infrastructures that inoculate communities from violence. The purpose of this mixed methods study was to evaluate an intervention designed to facilitate disengagement from gangs and desistance from crime. An impact evaluation, based on a preregistered randomized controlled trial, was paired with a process evaluation, based on field observations and interviews, of the Gang Reduction Initiative of Denver’s centerpiece intervention that uses multidisciplinary teams and street outreach workers to construct and implement coordinated case plans for high-risk gang members. The results of the impact evaluation revealed that clients assigned to the intervention were nearly 70 percent less likely to perpetrate violence yet were three times more likely to identify as gang members. The results of the process evaluation indicated that multidisciplinary teams were effective in securing services for their clients. Despite their limited training and heterogenous strategies, street outreach workers were viewed positively by their clients and were observed to prioritize behavioral over identity change. These findings are situated within longstanding tensions concerning the use of outreach workers and the targeting of gang behavior and/or identity in violence reduction strategies, along with the emergence of community violence intervention and prevention supported by large-scale federal investment.