IntroductionAlthough rare, the atrioesophageal fistula is one of the most feared
complications in radiofrequency catheter ablation of atrial fibrillation due
to the high risk of mortality.ObjectiveThis is a prospective controlled study, performed during regular
radiofrequency catheter ablation of atrial fibrillation, to test whether
esophageal displacement by handling the transesophageal echocardiography
transducer could be used for esophageal protection.MethodsSeven hundred and four patients (158 F/546M [22.4%/77.6%];
52.8±14 [17-84] years old), with mean EF of
0.66±0.8 and drug-refractory atrial fibrillation were submitted to
hybrid radiofrequency catheter ablation (conventional pulmonary vein
isolation plus AF-Nests and background tachycardia ablation) with
displacement of the esophagus as far as possible from the radiofrequency
target by transesophageal echocardiography transducer handling. The
esophageal luminal temperature was monitored without and with displacement
in 25 patients.ResultsThe mean esophageal displacement was 4 to 9.1cm (5.9±0.8 cm). In 680
of the 704 patients (96.6%), it was enough to allow complete and safe
radiofrequency delivery (30W/40ºC/irrigated catheter or 50W/60ºC/8 mm
catheter) without esophagus overlapping. The mean esophageal luminal
temperature changes with versus without esophageal displacement were
0.11±0.13ºC versus 1.1±0.4ºC respectively,
P<0.01. The radiofrequency had to be halted in 68% of
the patients without esophageal displacement because of esophageal luminal
temperature increase. There was no incidence of atrioesophageal fistula
suspected or confirmed. Only two superficial bleeding caused by
transesophageal echocardiography transducer insertion were observed.ConclusionMechanical esophageal displacement by transesophageal echocardiography
transducer during radiofrequency catheter ablation was able to prevent a
rise in esophageal luminal temperature, helping to avoid esophageal thermal
lesion. In most cases, the esophageal displacement was sufficient to allow
safe radiofrequency application without esophagus overlapping, being a
convenient alternative in reducing the risk of atrioesophageal fistula.
Despite the differences in terms of pathologies between the ICD-LABOR (Latin American bioelectronic ongoing registry) and randomized ICD trials, a parallel evolution in all cause mortality and cardiac mortality was observed. Independent risk factors for mortality included age >70 years, male gender, NYHA III/IV, and ejection fraction <0.30. The etiology of heart disease (Chagas vs Coronary Disease) was not found to be a risk factor.
Despite having a huge benefit in enabling heart rate control, cardiac pacing by stimulating the right ventricular apex causes an artificial iatrogenic left bundle-branch block-like syndrome. As a result, QRS widening and cardiac wall desynchronization occurs. The problems caused by this undesirable pacemaker side effect have been ignored, as they are counteracted by the great benefit of cardiac rate correction. However, the compelling evidence about its harmful effect presented in this article cannot be disregarded and should start an attitude change toward alternate sites of ventricular pacing and preclusion of the right ventricular apex stimulation.
The SM in sinus rhythm can be used in the ablation of AF nests. During the AF, the AF nests present a reactive-resonant pattern and the compact myocardium is passive, stimulated by the high frequency of the BT. After the ablation of the AF nests and the BT, it was not possible to reinduce the sustained AF. The Ablation of AF nests outside the pulmonary veins showed to be safe and highly effective in the cure and/or clinical control of the AF.
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