The use of medicinal plants reflects the reality of a part of human history. The Brazilian population with limited access to public health programs led to the development and conservation of ethnobotanical knowledge-rich information regarding medicinal plants. However, popular wisdom lacks systematization so that it can correctly use it. Herein we present the Piranhea trifoliata (family Picrondendraceae), an Amazonian plant with a wide variety of molecules with biological effects. The antimalarial effect was the dominant description observed in the studies used for this review, followed by antifungal and antioxidant actions. This review provides a synopsis of the recent literature exploring the extracts from P. trifoliata that could efficiently prevent pathologies associated with cellular maintenance mechanisms during malaria or fungal infection and oxidative stress.

The objective of this study was to determine the seroprevalence of Helicobacter pylori infection in Itapeuá, Municipality of Coari, in the rural area of Amazonas State, Brazil. A seroprevalence of 82% was observed in a sample of 100 individuals examined. The infection rate verified in children and adolescents (53%; 44/82) was higher than in adults and elderly (47%; 39/82). Stratified sampling of the population in age intervals of ten years showed that the age group 11-20 presented the highest frequency level (31%) and the highest infection rate (90%; 28/31). This association was relevant (G-test = 16.9312, p = 0.0095), and the prevalence of infection among male adults and female children (G-test = 9.8576, p = 0.0072) showed that individuals in these age groups are more susceptible to this bacterial infection.

Several compounds extracted from medicinal plants and their active ingredients can relieve symptoms and even cure diseases, although they occasionally have adverse effects. The knowledge of their properties has been transmitted over the centuries within and among human communities. Himatanthus sucuuba is an Amazon plant that has its value attributed to the different herbal impacts popularly reported. This review presents significant biological activities such as antibacterial, antifungal, anthelmintic, antileishmanial, anti-inflammatory, analgesic, antidepressant, immunoregulatory, cytotoxic, and genotoxic. Thus, provides a synopsis of the literature exploring the extracts of H. sucuuba to the Amazon region that could efficiently prevent pathologies associated with leishmaniosis, infection for bacteria or fungus, depression, oxidative stress, and cytotoxicity or genotoxicity.