O objetivo do trabalho foi avaliar clinicamente ou macroscópica e histologicamente as reações teciduais produzidas pelo implante da abraçadeira autoestática de náilon transparente e colorida em ratos Wistar. Foram utilizados 48 ratos Wistar hígidos machos, com idade de 16 semanas e massa corpórea entre 350 e 450 gramas. Os animais foram alocados em dois grupos de 24 animais: Grupo 1 –– ratos submetidos ao implante do fio de sutura náilon cirúrgico monofilamentar (Grupo Controle); Grupo 2 - ratos submetidos ao implante de fragmento da abraçadeira autoestática de náilon transparente e colorida (Grupo Experimental). As implantações no grupo controle foram realizadas com 5 mm de fio de sutura náilon cirúrgico monofilamentar entre o músculo carnoso e paravertebral esquerdo; e no grupo experimental foram implantadas 5 mm de fragmento da abraçadeira autoestática de náilon transparente e colorida, na mesma região em lados opostos e equidistantes da coluna vertebral. Oito ratos de cada grupo foram submetidos à eutanásia para realização da biopsia excisional dos implantes para posterior exame histológico em três momentos: sétimo dia, 15º dia e 90º dia após a implantação. A avaliação de infecção e/ou inflamação foi realizada a cada 24 horas. Lesões circunscritas multifocal ao redor dos três implantes foram observadas em 46,7% dos ratos, entre o primeiro e sétimo dia após as implantações. Reação inflamatória aguda esteve ausente em todos os grupos nos momentos avaliados. Reação inflamatória crônica foi observada no grupo do fio de sutura e das abraçadeiras em todos os momentos de avaliação, excetuando ao sétimo dia após a implantação no grupo das abraçadeiras autoestáticas transparentes. Reação inflamatória mista foi observada no grupo do fio de sutura e das abraçadeiras ao sétimo e 15º dia. Os implantes do fio de sutura náilon cirúrgico monofilamentoso (Grupo Controle), das abraçadeiras autoestáticas de náilon transparente e colorida (Grupo Experimental) apresentaram induziram reações clínicas ou macroscópicas e histológicas similares em ratos Wistar num período de 90 dias.
Background: Pharmacodermia is a drug reaction that manifests itself on the skin and mucous membranes. The main drugs that cause pharmacodermia are β-lactam antibiotics. It has a rare occurrence in dogs and may present different clinical signs. Ozone therapy is used to treat various conditions, such as infections and inflammatory diseases. This therapy acts through oxidative stress generating a positive inflammatory response to the body and stimulating the formation of granulation tissue and angiogenesis. Since pharmacodermia is rare in dogs and reports of ozonized sunflower oil and ozone for treat pharmacodermia is are rare in the literature, this paper aimed to report the use of ozonized sunflower oil in the treatment of pharmacodermia in a young female Rottweiler dog assisted and treated at a private veterinary clinic in Garanhuns, Pernambuco, Brazil. Case: A 2-year-old Rottweiler female, weighting 53.3 kg was attended at a private veterinary clinic in Garanhuns (Pernambuco -PE) with a history of dystocia. The dog was submitted to ovary-hysterectomy under general anesthesia. After anesthesia recovery was prescribed omeprazol (1 mg/kg, orally (P.O) SID for 10 days), cephalexin (20 mg/kg, P.O. BID for 10 days), tramadol hydrochloride (4 mg/kg, P.O. BID for seven days), carprofen (4.4 mg/kg, P.O. SID for three days), and the use of Elizabethan collar. Furthermore, for topical treatment was described chlorhexidine digluconate (0.2%) and ointment of allantoin and zinc oxide, SID, for 10 days. Seven days after the surgical procedure, the owner's dog reported by a telephone call the appearance of wounds in the dorsal region of the dog. Ten days after surgery, the dog returned to the veterinary clinic for stitches removal and wounds evaluation. During the physical examination, observed the presence of two cutaneous wounds, one located in the cervicothoracic region and the other wound was identified in the thoracic region and presence of pain during palpation. The wounds presented purulent secretion, pink coloration, and presence of necrosis. No changes were observed in the physiological parameters during the physical examination. The owner reported normophagia, ingestion of water, normal defecation and urine. The wound region was clipped, and prescribed topical chlorhexidine digluconate (2%), allantoin with zinc oxide ointment every 8 hours, amoxicillin and clavulanate potassium (20 mg/kg, P.O. BID for 10 days), and dipyrone (20 mg/kg P.O. BID for five days). Five days after the beginning of the second treatment the owner reported no improvement and the increased of the lesion, although the dog presented normophagia, ingestion of water, normal defecation, and urine. Thus, according to a therapeutic history of the use of cephalexin and amoxicillin with clavulanate potassium, both belongings to the β-lactamic antibiotic, the clinical diagnosis of pharmacodermia was determined. Wound cleaning and debridement were performed It has been recommended to suspend the previous treatment, and prescribed the use of ozonized sunflo...
Skin grafting refers to a reconstructive method used in cases of integumentary discontinuity, being an excellent option for covering lesions. Surgical defects resulting from the excision of cutaneous neoplasms are its main indication. A 13-year-old male SRD dog was treated at the São Lucas Veterinary Hospital, in the city of Ji-Paraná - RO, during the physical examination, a neoplastic mass was noticed on the lateral face of the left forelimb. The tegumentar grafting technique was chosen due to the length of the surgical cut and the scarcity of skin to approximate the incised edges, so the skin graft was removed from the left lateral region of the chest.
Mycobacterium bovis is the main cause of bovine tuberculosis, being one of the main zoonoses that have a great economic and public health impact. The objective of this research was to evaluate the occurrence of bovine tuberculosis in carcasses through post mortem inspection in a slaughterhouse under the Federal Inspection System (SIF) located in the central region of Rondônia. The total number of slaughtered cattle, carcasses condemned for tuberculosis, the quarterly average and the total average of bovine tuberculosis occurrence were analyzed using descriptive statistics. The occurrence of lesions suggestive of bovine tuberculosis in carcasses in the slaughterhouse studied confirms the importance of inspection and inspection of meat.
Corneal ulcer is considered an emergency, which can lead to loss of vision if left untreated. Among the surgical techniques of choice, the pedicled conjunctival flap is a procedure that provides mechanical and vascular supply of the conjunctiva to the corneal lesion. The aim of this study is to report a case of bilateral descemetocele in a nine-month-old female dog, Shih Tzu, treated at São Lucas Veterinary Hospital of Ji-Paraná. Initially, the treatment was systemic and topical drug therapy, after 72 hours, surgery was performed in both eyes and temporary tarsorrhaphy only in the right eye, later following the entire healing process.
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