Gestational diabetes (GD), defined as carbohydrate intolerance with onset or first recognition during pregnancy, has a prevalence of 7% and is a growing problem worldwide. Infants born to mothers with GD are more likely to be large for gestational age, incur traumatic birth injury, require a stay in the intensive care unit and develop postnatal metabolic disturbances. As the worldwide epidemic of obesity worsens, more women are entering pregnancy with metabolic alterations and preexisting insulin resistance, which is heightened by the hormonal milieu of pregnancy. The Hyperglycemia Adverse Pregnancy Outcome (HAPO) study has clearly shown that GD-related complications correlate with glycemic control. We will review the current understanding of the physiology of GD and the screening and treatment guidelines that are commonly utilized in clinical care. In addition, we will discuss the need for development of multiparametric models combining maternal clinical risk factors and biomarkers early in pregnancy to better stratify and predict risk of GD-related complications and offer targeted intervention.
We report a case of primary breast lymphoma which was incidentally detected in a 71 year-old-female while investigating for pulmonary embolism with Computed tomography angiograph (CTA) of the chest. Primary breast lymphoma has no specific imaging features however may have better prognosis than breast carcinoma and management is non-surgical.
Aortocaval fistula is uncommon and often associated with a ruptured iliac or abdominal aortic aneurysm. It has a high mortality secondary to the aneurysmal rupture but also to a high output heart failure. Open surgery has been the standard; however, endovascular management has emerged with lower mortality. We present a patient with a ruptured iliac aneurysm and an inferior vena cava fistula successfully treated with an endograft with embolization of the right hypogastric artery. The patient arrested on induction and was resuscitated with aortic balloon inflation. Endovascular therapy can be safely used in the management of iliac/aortocaval fistula.
Congenital anomalies of the kidney and the urinary tract such as renal agenesis and ectopic ureter have complex development. These anomalies have variable presentations and associations. In this report, we highlight the case of a young man with congenital renal agenesis presenting for a urinary tract infection. Abdominal and pelvic computed tomography imaging revealed the rare association of renal agenesis with contralateral ectopic ureter and subsequent hydroureteronephrosis. A urinary tract infection can be the presenting complication of such association, and a long follow-up is needed to anticipate the management.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.