No abstract

(1) An optimum AV delay is an important component of hemodynamic performance; and (2) AV sequential pacing at rest with an optimum AV delay may provide better hemodynamic performance than atrial pacing with intrinsic ventricular conduction when native AV conduction is prolonged > 220 msec.

A new endovascular spiral lead that takes advantage of the anatomy of the cardiac branches of the vagus nerve in the SVC was developed. VNS using ESVL produced significant HR slowing at voltages slightly below the highest pulse generator output of 7.5 V, which may be suitable for long-term implantation.

Patients with complete heart block on a spontaneous, or iatrogenic basis who also have recurrent supraventricular tachycardias, particularly atrial fibrillation and flutter, are often difficult to manage. Various techniques include: independently programmable maximum tracking and maximum sensor rates, limiting the maximum atrial tracking rate to the sensor response of the pacemaker, or automatically switching from DDDR to VVIR based upon the sensed atrial rate. This article will describe a mode switch algorithm that allows for an independently programmable atrial tachycardia detection rate (ATDR). This allows mode switching to occur only in response to the patient's pathological tachyarrhythmia, and not during normal upper rate response. The ATDR is based upon a filtered atrial rate, which will prevent an isolated premature beat from initiating the algorithm. In addition, the unit can be programmed to switch to either DDI, DDIR, VVI, or VVIR. Extensive event counters in the pulse generator allows the system to record and store the number of algorithm activations, the average atrial rate which triggered each mode switch, and the duration of the mode switch. These reports are accessible at each follow-up visit.

Dual chamber rate responsive pacing may be an ideal mode but may result in high current drain and premature battery depletion. To minimize battery drain during exercise, this study compared a combination pacing mode of DDD and ventricular rate responsive pacing (VVIR). Nine patients were studied who had complete heart block, sinus rhythm, DDD pacemakers, and a reduced mean left ventricular ejection fraction of 44%. Patients were exercised in DDD, VVIR, and a combination of DDD at low heart rates and VVIR at mean heart rates over 89 bpm. Blood pressure, heart rate, exercise duration, work rate, oxygen uptake, anaerobic threshold, and oxygen pulse were measured. There was no difference in symptoms or in mean cardiopulmonary function indices including exercise duration 10.7, 10.3, 10.3 minutes; heart rate 127, 133, 136 bpm; oxygen uptake 1.4, 1.5, 1.5 L/minute; or anaerobic threshold 5.6, 5.5, 5.7 minutes (p greater than 0.05) in any mode. A pacemaker that provides atrioventricular synchrony at low heart rates with ventricular rate responsiveness at high heart rates may be an alternative mode for some patients.