The reference nutrient intake for vitamin D in people aged ≥4 years is 10 μg/day in the UK, which contrasts with the recommended daily allowance of 15 μg/day for people aged 1-70 years in the USA. Using modelling of published data, we compared 95% confidence intervals for serum concentrations of 25-hydroxyvitamin D3 (25(OH)D3) attained in response to these two doses. 97.5% of those taking 10 μg/day vs. 15 μg/day were predicted to attain circulating 25(OH)D concentrations >44 nmol/L vs. 50 nmol/L, respectively.
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