Ehlers-Danlos Syndrome is a very rare, genetically and clinically heterogeneous, heritable disorder characterized by abnormal collagen synthesis. There are at least thirteen subtypes with variable inheritance patterns, majority being autosomal dominant. The cardinal features include joint hypermobility, skin hyperextensibility, and soft connective tissue fragility. Radiologically, hemarthrosis, precocious osteoarthritis, arachnodactyly and kyphoscoliosis are seen involving the skeleton. We present a case of an 18-year-old girl with joint hypermobility, easy bruisability, joint pain and lax skin. She was undiagnosed until her adulthood. Radiological investigations revealed characteristic arachnodactyly, kyphoscoliosis and precocious osteoarthritis which led to her diagnosis of Ehlers Danlos syndrome.
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