BACKGROUND
While there are reports of acute ischemic stroke (AIS) in coronavirus disease 2019 (COVID-19) patients, the overall incidence of AIS and clinical characteristics of large vessel occlusion (LVO) remain unclear.
OBJECTIVE
To attempt to establish incidence of AIS in COVID-19 patients in an international cohort.
METHODS
A cross-sectional retrospective, multicenter study of consecutive patients admitted with AIS and COVID-19 was undertaken from March 1 to May 1, 2020 at 12 stroke centers from 4 countries. Out of those 12 centers, 9 centers admitted all types of strokes and data from those were used to calculate the incidence rate of AIS. Three centers exclusively transferred LVO stroke (LVOs) patients and were excluded only for the purposes of calculating the incidence of AIS. Detailed data were collected on consecutive LVOs in hospitalized patients who underwent mechanical thrombectomy (MT) across all 12 centers.
RESULTS
Out of 6698 COVID-19 patients admitted to 9 stroke centers, the incidence of stroke was found to be 1.3% (interquartile range [IQR] 0.75%-1.7%). The median age of LVOs patients was 51 yr (IQR 50-75 yr), and in the US centers, African Americans comprised 28% of patients. Out of 66 LVOs, 10 patients (16%) were less than 50 yr of age. Among the LVOs eligible for MT, the average time from symptom onset to presentation was 558 min (IQR 82-695 min). A total of 21 (50%) patients were either discharged to home or discharged to acute rehabilitation facilities.
CONCLUSION
LVO was predominant in patients with AIS and COVID-19 across 2 continents, occurring at a significantly younger age and affecting African Americans disproportionately in the USA.
INTRODUCTIONCervical cancer is a leading cause of morbidity and mortality in women especially India. This is the second most common cancer among women worldwide with an estimated 530,000 new cases & 275,000 deaths with overall incidence: mortality ratio of 52%. 1 Developing countries where it is the most common cancer among women, it accounts for 88% of the cases. Cases & deaths have declined markedly in the last 40 years in the most industrialized countries partly owing to reduction in risk factors but mainly as a result of extensive screening programs. More limited improvements have been observed in developing countries where persistently high rates tend to be the rule.2 It is estimated that during 2012; 134,420 new cases of cancer cervix have occured in the country and about 72,825 women died of the disease.3 In West Bengal, the incidence rate of cervical cancer is 27 ABSTRACT Background: Cervical cancer is a leading cause of morbidity and mortality in women especially India. The mainstay of prevention rests on early detection of cases through screening. So, this study aims to determine the knowledge of cervical cancer screening, Human papilloma virus & its vaccination status. Methods: This was an observational study of cross-sectional design conducted among the adult reproductive aged women (18-45 years) visiting Gynaecology OPD at ESI-PGIMSR and ESIC Medical College and Hospital, Joka. A pre-designed and pre-tested interview schedule was prepared. Face to face interview was conducted in local language.
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