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SummaryThe capacity of brain and peripheral organs to accumulate dopamine following intraperitoneal 1-dopa was not impaired in rats whose catecholamine-containing nerve terminals had been destroyed by pretreatment with intracisternal or intraperitoneal 6-hydroxydopamine. These findings indicate that the uptake of exogenous 1-dopa and its conversion to dopamine are not restricted to cells that normally synthesize and contain catecholamines.

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