In Mexico, plasma colloid osmotic pressure has been a key issue in the study of pregnant women for more than two decades. Clinical investigations have allowed to know their values in the open population, as well as in women with normal pregnancy, physiological puerperium, severe preeclampsia, HELLP syndrome, and eclampsia. The relationship of plasma colloid osmotic pressure with mean arterial pressure (Briones index), capillary leak syndrome and the accumulation of fluid in serous cavities (pleural effusion, and ascites) have also been reported. We reviewed the database of PubMed, The Cochrane Library, OVID, Science Direct, Google Scholar, Artemisa, LILACS, and IMBIOMED from 1997 to 2018 with the following keywords: serum albumin, plasma colloid osmotic pressure, capillary leak syndrome, Briones index, pleural effusion, ascites, severe preeclampsia, HELLP syndrome, eclampsia, and obstetrics critical care. Inclusion criteria were systematic reviews, meta-analysis, clinical controlled trials, and articles with evidence-based medicine methodology with strong recommendations. We included 12 Mexican articles. The objectives of the present investigation were to review the medical literature on plasma colloid osmotic pressure in preeclampsia reported from 1997 to 2018, describe the treatment with human albumin and the perspectives of the research in the following years.
