SARS-CoV-2 infection has had a major impact on donation and transplantation. Since the cessation of activity two years ago, the international medical community has rapidly generated evidence capable of sustaining and increasing this neccesary activity. This paper analyses the epidemiology and burden of COVID-19 in donation and transplantation, the pathogenesis of the infection and its relationship with graft-mediated transmission, the impact of vaccination on donation and transplantation, the evolution of donation in Spain throughout the pandemic, some lessons learned in SARS-CoV-2 infected donor recipients with positive PCR and the applicability of the main therapeutic tools recently approved for treatment among transplant recipients.

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Aim The aim of this study is to determine the reliability and validity of the Humour Styles Questionnaire (HSQ) in a sample of Spanish healthcare professionals. Design A cross‐sectional study. Methods The version of HSQ translated into Spanish by Cayssials and Pérez was used to validate on a sample of healthcare professionals (N = 250). The reliability analysed the Crombach's α coefficient and Pearson's correlation coefficient between the factors and the total scale score. The Exploratory Factor Analysis was carried out with Kaiser's criteria for the extraction of factors with Varimax rotation. Results HSQ in this study sample reproduced the similar structure of the original version with four factors (affiliative, self‐enhancing, aggressive and self‐defeating humour). These factors explained 44.46% of the total variance and Cronbach's ranged from 0.64–0.79. Global HSQ scale reliability was 0.82. Conclusion The HSQ is a valid and reliable instrument for assessing humour in healthcare professionals.

Resumen. Introducción: Las úlceras de pie diabético son una de las mayores causas de incapacidad en pacientes con Diabetes Mellitus (DM). La Terapia de Presión Negativa (TPN) se presenta como uno de los mejores procedimientos en su tratamiento, estimulando la granulación, drenando el exudado y reduciendo el edema. Objetivos: Realizar una revisión sistemática acerca de la efectividad y la aplicabilidad clínica real del uso de la TPN en las úlceras de pie diabético. Material y métodos: Búsqueda bibliográfica realizada en noviembre de 2016 en las bases de datos PubMed, CINAHL, SciELO y Web of Science, con las palabras clave ("negative pressure wound therapy" OR "vacuum assisted closure" OR "vacuum sealing drainage") AND ("diabetic foot" OR "diabetic wound" OR "diabetic ulcer"). Se seleccionaron las publicaciones cuyos diseños fueran ensayos clínicos aleatorizados (ECA), según los criterios de la declaración PRISMA, y analizaran el objetivo planteado. Resultados: Se encontraron 12 ECAs de calidad metodológica suficiente. 7 de los ECAs utilizaron como variable principal la superficie del lecho de la herida y 5 utilizaron el tiempo hasta la granulación. Conclusiones: La TPN consigue una mayor superficie de tejido de granulación, un menor tiempo de cicatrización y una diminución del tiempo hasta que comienza la granulación. Palabras clave: pie diabético; Terapia de Presión Negativa. [en] Effectiveness of negative pressure therapy in diabetic foot ulcer: systematic review Abstract. Background: Diabetic foot ulcers are one of the major causes of disability in patients with Diabetes Mellitus (DM). The Negative Pressure Wound Therapy (NPWT) is one of the major procedures in his treatment, estimulating granulation, draining exudate and reducing edema.e Objectives: To realize a systematic review about the effectiveness and the real clinical application of NPWT use in diabetic foot ulcers.

Précis: Childhood glaucoma produces alterations in the postnatal development and function of various ocular structures, including the cornea. Childhood glaucoma patients present lower corneal transplant survival rates. Our series shows outcomes of corneal transplant in childhood glaucoma with survival rates of 29% at 2 years. Objective: To investigate the surgical outcome of different types of keratoplasty in eyes with childhood glaucoma. Patients and Methods: A retrospective review was made of the medical records from 17 eyes of 15 patients who were diagnosed with childhood glaucoma and received a corneal transplantation between January 2010 and July 2020. Patient demographics, intraocular pressure, previous ocular surgery, comorbidities, corneal transplant surgery, and follow-up outcome were collected. The primary efficacy endpoint was graft survival (in months) until failure, the latter being considered as irreversible loss of corneal transparency. Secondary efficacy points were the need for an increase in topical hypotensive therapy and the need for additional surgery. Results: Seventeen eyes of 15 patients were included, 11 eyes (10 patients) with primary congenital glaucoma and 6 with other types of childhood glaucoma. Corneal transplantation was performed at the mean age of 23.76 ± 14.86 years. At the time of the transplantation, the number of topical medications was 1.35 ± 1.27, intraocular pressure was 15.00 ± 8.34 mm Hg, and patients had received up to 7 glaucoma surgeries. Descemet stripping automated endothelial keratoplasty was performed in 13 eyes (76%) and penetrating keratoplasty in 4 (24%). After surgery, 7 (41%) eyes required increased topical treatment and 2 (12%) glaucoma surgery. Twelve eyes (71%) developed graft failure at 24 months, the mean time of survival being 13.88 ± 8.25 months. Conclusions: Management of corneal decompensation in childhood glaucoma poses a challenge. In this series of childhood glaucoma with corneal transplantations, the survival rate was 29% at 24 months.