Sewer systems are large-scale systems that collect and transport stormwater and sanitary sewage out of urban areas. Sewer systems are mainly operated using pumping stations and pollutants are removed from sewage by treatment plants before water is released into the environment. When a sewer overflow occurs, e.g., caused by a strong rainfall, sewage is discharged directly into the environment without any treatment. An efficient use of storage capacities and pumping stations can help to minimize the environmental pollution caused by sewer overflows. In this paper a nonlinear predictive control approach is presented to improve the operation of sewer systems. To deal with the nonlinear and nondifferentiable features of the prediction model used, a pattern search method is proposed to solve the underlying optimization problem. The technique proposed is implemented on a part of the sewer system of Bogotá, Columbia. Simulation results illustrate the potential of the approach.

In this paper water distribution systems and sewer systems are considered. Both can be seen as complementary networks: water distribution systems supply the commodity to consumers while sewer systems drain the wastewater which is produced by domestic usage and industrial facilities. In the water distribution case an application of a distributed control scheme for management of urban water supply networks is proposed. The scheme is based on local model predictive control (MPC) and a parallel coordination that implements cooperation among local MPC controllers. For the sewer system case a nonlinear predictive control is presented. To deal with the nonlinear and nondifferentiable features of the used predictor model, a direct search method is proposed to solve the optimization problem. Both cases are based on the Bogotá's networks and results illustrate the potential of the approaches.

Enfermedad pulmonar tromboembólica secundaria a mutación factor V de Leiden y deficiencia de antitrombina III Pulmonary embolism disease due Leiden factor V mutation and antithrombin III deficiency Doença pulmonar tromboembólica secundária a mutação do fator V de Leiden e deficiência de antitrombina III

Disfunción en la plasminogénesis en paciente críticamente enfermo con infección polimicrobiana asociado a deficiencia de glicoproteínas Plasminogenesis disfunction in critical ilness patient with polimicrobial infection associated glycoproteins deficiency Disfunção da plasminogênese em paciente crítico com infecção polimicrobiana associada a deficiência de glicoproteínas