Conyza aegyptiaca (L.) Dryand ex. Aiton (C. aegyptiaca) is used in West Africa for diabetes treatment without any scientific study and adequate therapeutic indications. Our previous study shows that C. aegyptiaca extract is nontoxic on larvaes and prevent hepatic glucose liberation in rat. In the present study, we evaluated the acute oral toxicity of C. aegyptiaca aqueous and ethanolic extracts at a unique dose of 300 and 2000 mg/kg body weight (bw). We also determined its effect on blood glucose level by the Oral Glucose Tolerance Test (OGTT) on albinos Wistar rats. Acute oral toxicity showed no mortality and no toxic effect throughout the study. There were no significant changes in glycaemia, creatinine, lipids, AST, ALT and ions Ca 2+ , Cl -, Na+, K + , and Mg 2+ levels when compared to control. OGTT showed that only the aqueous extract at the dose of 500 mg/kg bw normalized blood glucose level 75 min after OGTT induction compared to 60 min for Glybenclamide. Results suggest that C. aegyptiaca aerial part extract is safe and possesses anti-hyperglycemia potential. Further studies are needed to isolate and characterize the plant active component and to test it for diabetes treatment.

Malgré la hausse de la température atmosphérique pendant la grande saison de pluies, la Fédération Congolaise de Football (FECOFOOT) organise les matchs à 14 heures. Dans le but d’évaluer les paramètres physiologiques des footballeurs par poste de jeu et la distance totale qu’ils parcourent au cours d’un match éprouvant de football en république du Congo. Un match test a été organisé à une température de 39 °C et une humidité relative de 60 %. La fréquence cardiaque d’effort (170,4 ± 8,73 bpm), la température corporelle centrale (37,06 ± 0,20 °C) ainsi que la quantité d’eau consommée au cours du match (2,28 ± 0,37 L) des attaquants étaient plus élevées que les autres joueurs. Par contre, la perte hydrique (3,55 ± 0,55%), la dépense énergétique (868,00 ± 99,52 kcal) et la distance totale parcourue (8,95 ± 0,47 km) des milieux de terrain étaient supérieures aux autres joueurs. Le football pratiqué dans un environnement chaud et humide entraine une contrainte physiologique élevée responsable de la contre performance des footballeurs.  Mots clés : Perte hydrique, performance, footballeur, climat chaud et humide, R. Congo.   English Title: Physiological responses by playing position of elite footballers during a challenging match in a hot and humid environment Despite the rise in atmospheric temperature during the great rainy season, the Congolese Football Federation (FECOFOOT) organizes the matches at 2 pm. For the purpose of evaluating the physiological parameters and the total distance travelled by footballers per playing position during a challenging football match in the republic of Congo. A test match was held in a hot and humid environment with a temperature of 38 °C and a relative humidity of 60%. The exertion heart rate (170.4 ± 8.73 bpm), core body temperature (37.06 ± 0.20 °C) and the amount of water consumed during the match (2.28 ± 0.37 L) of the strikers were higher than those of the other players. In contrast, water loss (3.55 ± 0.55%), energy expenditure (868.00 ± 99.52 kcal) and total distance travelled (8.95 ± 0.47 km) from midfielders were higher than other players. Football played in a hot and humid environment leads to a high physiological stress responsible for the counter-performance of footballers. Keywords: Water loss, performance, football player, hot and humid climate, R. Congo.

The present study aim was to assess the preventive effects of Ananas comosus juice consumption on the risk factors of obesity in female Wistar rats. 108 rats were tested for 90 days. After randomization, they were shared out into six groups including four experimental groups (GTc, GPlp, GEns and GBrS) and two control groups (+ CT G and CT G −). The control group consumed 1.20 ml of distilled water, the experimental rats received in oral, 1.20 ml of drinks made from the different parts of Ananas comosus fruit. The measurements of morphometric and biochemical parameters were carried out on Day 0 (D0), Day 30 (D30), Day 60 (D60) and Day 90 (D90). The analysis showed that compared to the positive control rats, the consumption of the various drinks slowed down significantly (P < 0.001); the evolution of the morphometric and biochemical parameters likely to induce obesity in experimental rats which have an increase in a protective factor (HDL; P < 0.001). These results indicate that consumption of different parts of Ananas comosus's juices had preventive effects on risk factors related to obesity. Moreover, the fruit juice treatment has been found to be more effective.

The objective of this study is to assess the combined effects of exercise and consumption of Cymbopogon citratus on anthropometric and hemodynamic parameters in obese women. Forty (40) obese women were divided into four groups: group 1 (G1) was subjected to physical exercises and  consumption of Cymbopogon citratus; group 2 (G2) had consumed only Cymbopogon citratus;  group (G3) was practiced only physical exercises and group 4 (G4) have neither consumed Cymbopogon citratus and nor practiced physical exercises. The anthropometric and hemodynamic parameters were measured on three days : D0, D30 and D60. The results showed various modifications of the variables studied. In group G1, weight and Body Mass Index (BMI) decreased significantly (p < 0.001), as well as fat index and size circumference (p < 0.01). Fat mass, Hip circumference, blood pressure and rest heart rate were significantly reduced (p < 0.05). For G2, weight and BMI decreased (p < 0.01). Loss of muscle mass was observed (p < 0.05). In G3, weight decreased (p < 0.05) while muscle mass increased (p < 0.05). On analysis, the most significant changes were observed in group G1. Association of physical exercise and Cymbopogon citratus consumption has more beneficial effects on anthropometric and hemodynamic parameters in obese people.