These findings indicate that berberine-loaded fucose-conjugated nanoparticles exert an H. pylori clearance effect and effectively reduce gastric inflammation in an H. pylori-infected animal study.
Various types of wound dressings have been designed for different purposes and functions. Controlling bacterial burden in a wound during the early phase is important for successful wound repair. Once bacterial burden is under control, the active promotion of wound healing is another important factor for efficient wound healing. This study investigated the potential of three silver-containing dressings, namely KoCarbonAg(®) , Aquacel(®) Ag and Acticoat 7, in reducing bacterial survival and promoting wound healing. The ability of these dressings to block the entry of bacteria from external environment and retain intrinsic bacteria was studied in vitro. In addition, the study used a rat model to compare the healing efficiencies of the three dressings and investigate the quantity of collagen synthesis in vivo. In vitro results indicated that the silver-containing dressings prevented bacterial growth in wounds by blocking the entry of external bacteria and by retaining the bacteria in the dressing. In vivo study indicated that reduction in bacterial burden accelerated wound healing. Wounds treated by the silver-containing dressings showed better healing than those treated with gauze. Moreover, KoCarbonAg(®) further accelerated wound healing by promoting collagen synthesis and arrangement.
Porous activated carbon fiber (ACF) is prepared from oxidized polyacrylonitrile (PAN) fiber through three activation methods, which are traditional chemical activation, traditional physical activation, and ameliorative chemical activation. The samples under various high temperature heat treatments are used as electrode for the supercapacitor. The structure and electrochemical properties of these samples are then characterized by nitrogen adsorption at 77 K, X-ray diffraction (XRD), Raman spectrum, electron spectroscopy for chemical analysis (ECSA), Fourier transform infrared spectrometer (FTIR), cyclic voltammetry (CV), and galvanotactic charge/discharge, respectively. Once formed by the ameliorative chemical activation method, which is used for the electrodes of supercapacitors, the samples exhibited excellent capacitance characteristics in the 1 M H 2 SO 4 electrolyte and showed a high specific capacitance of 158 F/g, which is higher than the two traditional activation methods. HP20-1/3-900 presents a high specific capacitance of 173 F/g in 1 M H 2 SO 4 electrolyte and a high discharge capacitance of 180 F/g. Moreover, HP20-1/3-900 has near triangular shapes, reflecting their excellent charge/discharge capacitive performance. Results of this study demonstrate that the ameliorative activation process for preparing makes this activated carbon fiber a highly promising electrode material for industrial applications of supercapacitors.
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