CLS involves sudden loss of intravascular fluids into the interstitial spaces. CLS was described as a possible complication after SCT. Few studies report the incidence of CLS in pediatric populations. We aimed to assess CLS incidence, its risk factors, and impact on the survival. The clinical charts of patients <18 years of age transplanted at our institution between 2002 and 2012 were reviewed. CLS was defined by weight gain >3% in 24 hours and positive intake balance despite furosemide administration. In total, 234 patients underwent 275 allogeneic SCT procedures in the analyzed time frame. Fifteen patients developed CLS (5.4%). The probability of developing CLS was significantly increased in patients suffering from sepsis (14.3% vs 0.6%, P<.001). Patients with CLS exhibited an increased risk of acute GvHD in the first 30 days after SCT (10.8% vs 1.8%, P=.002). Ten of the patients with CLS required intensive care. CLS strongly impacts OS at day +100 after SCT and is a predictive factor of TRM at the same date (42.9% vs 5%, P<.0001). The biological relation among sepsis, GvHD, and CLS development in terms of cytokine release and endothelial damage warrants further studies.

No abstract

This urban ecocritical study reads the poetry of Edna St. Vincent Millay and William Carlos Williams in the context of the American street tree movement, a civic health and beautification program that advocated for the planting of shade trees along urban thoroughfares. It argues that both poets critique the ‘ideal’ street tree forwarded by the movement. In ‘City Trees,’ Millay presents a shade tree whose therapeutic effects are overwhelmed by the noise pollution in New York City, much like the speaker herself. In ‘Young Sycamore,’ Williams eschews the visual ideal of symmetrical, evenly-spaced shade trees in favor of a wily, asymmetrical organism that actively torques toward the light. By extension, these poets present city habitats as alternately more toxic and more wild than the street tree movement had imagined, a critique with ramifications for contemporary urban reforestation movements today.

No abstract

No abstract