Objectives: The aim of this study is to compare the mechanical characteristics of resins for 3D printers with the acrylic resins that have been used in Dentistry, according to the post-processing method. Materials and Methods: Using an SLA 3D printer (Form 2 – Formlabs, Massachusetts, USA), samples (discs) were produced with the printer’s resins, Dental SG®, Dental LT®, Clear®, and Grey®. Samples made of thermopolimerized and auto polymerized acrylic resins were produced as well (Gold Standart parameters). The Knoop Hardness (KH) tests were performed using microdurometer HMV-2 (Shimadzu, Kyoto, Japan). Results: The results showed the Dental SG resin presented the highest KH, compared with thermopolimerized acrylic resin, the Clear and Dental LT resins KH were compared with auto polymerized acrylic resin, and the non-post cured Grey resin (not for intraoral use), as well as the Dental LT resin, showed the lowest KH. Conclusions: Considering the hardness, the printer’s resins are comparable with the acrylic resins established, when the post-processing method is thoroughly followed. The absence of material’s post-processing reduce significantly the material’s hardness. Clinical relevance: Regarding the use of 3D printing in Dentistry, the development of materials adequate for the equipment, biocompatible for intraoral uses, and compatible mechanical proprieties are essential.