There is emerging data that patterns of motor activity early in neonatal life can predict impairments in neuromotor development. However, current techniques to monitor infant movement mainly rely on observer scoring, a technique limited by skill, fatigue, and inter-rater reliability. Consequently, we tested the use of a lightweight, wireless, accelerometer system that measures movement and can be worn by premature babies without interfering with routine care. We hypothesized that this system would be useful in assessing motor activity, in identifying abnormal movement, and in reducing the amount of video that a clinician would need to review for abnormal movements. Ten preterm infants in the NICU were monitored for 1 h using both the accelerometer system and video. A physical therapist trained to recognize cramped-synchronized general movements scored all of the video data by labeling each abnormal movement observed. The parameters of three different computer models were then optimized based on correlating features computed from accelerometer data and the observer’s annotations. The annotations were compared to the model’s prediction on unseen data. The trained observer identified cramped-synchronized general movements in 6 of the 10 infants. The computer models attained between 70% and 90% accuracy when predicting the same observer label for each data point. Our study suggests that mini-accelerometers may prove useful as a clinical tool assessing patterns of movement in preterm infants.

Objective-A prospective, cross-sectional, observational study in pre-and term infants was performed to compare multimodal measurements of body composition namely, limb ultrasound, bone quantitative ultrasound and dual X-ray absorptiometry (DXA).Patients and Methods-102 preterm and term appropriate for gestational age infants were enrolled from the newborn nursery and neonatal intensive care unit. Infants were included when they were medically stable, in an open crib, on full enteral feeds and within one week of anticipated discharge. Correlations among the various measurements of body composition were performed using standard techniques. A comparison between preterm infant (born at 28-32w) reaching term to term born infants was performed.Results and Conclusions-Limb ultrasound estimates of cross sectional areas of lean and fat tissue in a region of tissue (i.e., the leg) were remarkably correlated with regional and whole body estimates of fat free mass and fat obtained from DXA suggesting the potential usefulness of muscle ultrasound as an investigative tool for studying aspects of body composition in this fragile population. There was a weak but significant correlation between quantitative ultrasound measurements of bone strength and DXA derived BMD. Preterm infants reaching term had significantly lower body weight, length, head circumference, muscle and fat cross sectional area, bone SOS, whole body and regional lean body mass, fat mass and BMD compared to term born infants. Current post-natal care and nutritional support in preterm infants is still unable to match the in-utero environment for optimal growth and bone development. The use of relatively simple bedside, non invasive body composition measurements may assist in the understanding how changes in different components of body composition early in life affect later growth and development.

Purpose Mounting evidence shows that low birth weight and prematurity are related to serious health problems in adulthood, including increased body fat, decreased fitness, poor bone mineralization, pulmonary problems, and cardiovascular disease. There is data to suggest that increasing physical activity in preterm infants will have effects on short term muscle mass and fat mass, but we also hypothesized that increasing physical activity early in life can lead to improved health outcomes in adulthood. Because few studies have addressed the augmentation of physical activity in premature babies, the objective of this study was to evaluate the feasibility of whether caregivers (mostly mothers) can learn from nurses and other health care providers to implement a program of assisted infant exercise following discharge. Study Design and Methods Ten caregivers of preterm infants were taught by nurses, along with occupational therapists and other health care providers, to perform assisted infant exercise and instructed to conduct the exercises daily for approximately three weeks. The researchers made home visits and conducted qualitative interviews to understand the caregivers’ (mostly mothers’) experiences with this exercise protocol. Quantitative data included a caregiver’s daily log of the exercises completed to measure adherence as well as videotaped caregiver sessions, which were used to record errors as a measure of proficiency in the exercise technique. Results On average, the caregivers completed a daily log on 92% of the days enrolled in the study and reported performing the exercises on 93% of the days recorded. Caregivers made an average of 1.8 errors on two tests (with a maximum of 23 or 35 items on each, respectively) when demonstrating proficiency in the exercise technique. All caregivers described the exercises as beneficial for their infants, and many reported that these interventions fostered increased bonding with their babies. Nearly all reported feeling “scared” of hurting their babies during the first few days of home exercise, but stated that fears were alleviated by practice in the home and further teaching and learning. Clinical Implications Caregivers were willing and able to do the exercises correctly, and they expressed a belief that the intervention had positive effects on their babies and on caregiver-infant interactions. These findings have important implications for nursing practice because nurses are in key positions to teach and encourage caregivers to practice these exercises with their newborn babies.