Our findings imply that reducing the extent of self-stigmatization, especially the feeling of being alienated from society, could improve a negative attitude toward medication adherence in psychosis patients. Cognitive-behavioral therapy offers a variety of therapeutic strategies that could support patients in developing a more positive self-image and in more readily accepting antipsychotic medication as a tool for reaching personal life goals.

Risk reduction (e.g., aiming at CIT <15 h) and close surveillance of patients at risk appear to be crucial for allograft survival in the ESP.

In order to specifically encourage strengths on the part of the relatives and therefore improve their quality of life and their experiences of caregiving, their locus of control, social support and psychosocial functioning should be taken into consideration in concepts for the treatment of patients with psychosis.