Abstract. It is a matter of current study to determine potential climate changes in different parts of the world, especially in regions like a basin which has the potential to affect socioeconomic and environmental issues in a defined area. This study provides a comparison between several climate change indices trends of two very different basins in Mexico, one located in the northern arid region (the Conchos River basin) and the other in the southern humid area (the Usumacinta River basin). First, quality control, homogenization, and completion of the missing data were applied before calculating the climate change indices and their respective trends for the combined period 1961–1994. A clear warming signal was found for the two basins in addition to an increment in the DTR, in agreement with other studies in Mexico. Also, the Conchos River basin was found to be more humid and the Usumacinta River basin drier, in accordance to a supposed seesaw behavior indicated in previous analysis.