No abstract

Purpose Ethics review processes have become increasingly complex. The objective of this study was to explore the challenges currently faced in ethics reviews of clinical scientific research projects in China, with the goal of standardizing the structure of medical ethics committees and better protecting the rights and interests of research participants. Methods We reviewed and comprehensively analyzed the available literature discussing standardized ethics reviews of clinical scientific research projects. Results We identified the following problems: incomplete legislation, absence of supervision, vague review criteria, limitations of ethics committee competence, inadequate ethics consciousness, and poor tracking of reviews. In this paper, we suggest strategies for the development of future ethical reviews of clinical scientific research projects. Conclusion To standardize the ethics review process of clinical scientific research projects in China, it is necessary to establish relevant laws and regulations and implement supervisory responsibilities. Professional training of medical ethics committees is suggested as an effective way to improve the quality of ethics reviews.

This paper focuses on a multiproject resource allocation problem in a bilevel organization. To solve this problem, a bilevel multiproject resource allocation model under a fuzzy random environment is proposed. Two levels of decision makers are considered in the model. On the upper level, the company manager aims to allocate the company's resources to multiple projects to achieve the lowest cost, which include resource costs and a tardiness penalty. On the lower level, each project manager attempts to schedule their resource-constrained project, with minimization of project duration as the main objective. In contrast to prior studies, uncertainty in resource allocation has been explicitly considered. Specifically, our research uses fuzzy random variables to model uncertain activity durations and resource costs. To search for the optimal solution of the bilevel model, a hybrid algorithm made up of an adaptive particle swarm optimization, an adaptive hybrid genetic algorithm, and a fuzzy random simulation algorithm is also proposed. Finally, the efficiency of the proposed model and algorithm is evaluated through a practical case from an industrial equipment installation company. The results show that the proposed model is efficient in dealing with practical resource allocation problems in a bilevel organization.

No abstract

No abstract