ONO-8055 decreased post-void residual urine, probably by decreasing bladder capacity. The decrease in voiding pressure probably resulted from the lowered urethral pressure due to relaxation of the urethra. Thus, the novel EP2 and EP3 receptor dual agonist ONO-8055 has the potential to improve neurogenic underactive bladder.

Kv7 channels are likely to be implicated in inhibition of bladder mechano- and nociceptive sensory transduction. Neurourol. Urodynam. 36:280-285, 2017. © 2015 Wiley Periodicals, Inc.

No abstract

No abstract

A gradient-index rod whose length is a quarter of the periodic length works as a retroreflective element when its endface is coated with metal. This paper describes the experiment and theory on the reflectivity of such a rod and that of an array comprising seven or nineteen rods when they are illuminated by a Gaussian laser beam. We clarify how the reflectivity depends on the offset of the beam axis and the inclination angle of the axis. The far field pattern of the reflected wave is also investigated.