The use of oral moisturising gel containing anti-CA IgY for 1 month significantly reduces the number of C. albicans CFU present on swabs in older people.

Abstract:How transition of fluorine from orally applied sealant into dental matrix occurs and inhibits caries remains unknown. In the current study, we investigated mechanism of caries protection evaluating movement of fluoride ions from sustained-releasing fluoride sealant by EPMA from a crystallographic point and also from inorganic chemical view. Furthermore, we also evaluated differences of 2 kinds of sealant as a fluoride source, which have different releasing mechanism.Our results demonstrated that fluoride ion released from sealant abundantly accumulated in porous structure of tooth. From this result, it was considered that fluoride ion contributed to caries inhibition by infiltrating into porous structure appeared due to decalcification and enhancing pH environment. This result suggests thinking morphological viewpoint upon efficiency of fluorine in clinical dentistry for caries. When 2 different sealant materials were compared, GI-based sealant significantly released more fluoride ion than resin-based fluorine. Moreover GI-based sealant fluoride ion infiltrated significantly much more into decalcified area than resinbased fluorine. Thus in clinical dentistry, selection of GI-based fluoride ion at early periods and then alternation to long-term keeping resin-based fluorine should be considered to treat caries in a better way.

There are few studies reporting observation of invasion state of fluorine applied for white spots of enamel as well as healthy parts with a non-invasive method. Thus we used EPMA method to observe fluorine invasion state in a normal human tooth. We clearly observed that more fluorine infiltrated in the decalcified porous structured enamel organ as compared to normal healthy enamel. Our results showed that when teeth were considered to be protected from caries by application of oral fluorine, more fluorine accumulation occurred in the white spot area as compared to healthy enamel section, suggesting its useful clinical use.

Purpose: A water fluoridation program launched in the United States in 1945 has become a worldwide application for caries prevention. Although such a program is important in Japan, water fluoridation in large communities has not been established. This study aimed to develop safe small-scale water fluoride equipment that can be easily used to carry out water fluoridation programs in areas with children in long-term care facilities, and in developing countries without water supply facilities. Methods: Batch-type NaF addition adjustment equipment was manufactured as small-scale water fluoride equipment. The fluoride concentration of the adjusted water with this equipment was measured using an ion meter and a fluoride composite electrode. All 51 water quality standards set by the Ministry of Health, Labour, and Welfare of Japan were tested. Results:The fluoride ion concentration of the adjusted water was 0.7 mg/L and it was constant and stable. The adjusted water conformed to the water quality standard values of the Japanese Water Supply Law. Conclusion:Water produced with small-scale water fluoridation equipment had a fluoride concentration of 0.7 mg/L, which is the recommended concentration for caries prevention. The fluoride concentration was stable.