A hydroamination of unactivated alkynes and lithium bis­(fluorosulfonyl)­imide (LiN­(SO2F)2) is described under mild conditions, affording a single regioisomer of the sulfonyl fluorides. This method features broad functional group compatibility and delivers the target vinyl fluorosulfonimides in good to excellent yields. Moreover, gram-scale hydroamination of terminal and internal alkynes is achieved. Further transformations exploiting the reactivity of the vinyl fluorosulfonimide are subsequently developed for the synthesis of fluorosulfates and diphenyl sulfate.

An efficient one-pot, two-step process of N-propargylation of amino alcohols involving in situ protection and deprotection of the amino alcohols. This reaction is initiated by a Cu(I)catalyzed A 3 -coupling/annulation of an amino alcohol, formaldehyde solution, and a terminal alkyne. Subsequent

Metal-catalyzed hydrocarbofunctionalizations of alkynes or alkenes are well established. In contrast, metal-free strategies have few precedents. We report herein a multicomponent reaction that generates functionalized 1,4-dicarbonyl motifs via formal hydrocarbonylation...