In early 2021, roughly 6 months after the H7N9 H7‐Re3 and H7N9 rLN79 vaccine strains were introduced into China, we monitored a number of H7N9 subtype avian influenza viruses, which could have escaped vaccine‐induced immunity in live poultry markets (LPMs) in Yunnan, Hebei, Shanxi and Guangdong provinces, China. To investigate whether these viruses were a novel H7N9 variant of highly pathogenic avian influenza (HPAI) virus and whether they had the potential for further spread, we characterized the genetic evolution, antigenic divergence and pathogenicity of the viruses in the context of vaccine immunity. The results show further diversification in the HA gene of newly isolated HPAI H7N9 viruses compared with antigenic variants that emerged after the period of 2017–2019. There were clear antigenic differences between current vaccines and these viruses, and SPF broilers under vaccine protection could not resist virus challenges. Our study demonstrates that the current vaccine has insufficient protective capacity against the novel H7N9 variants under experimental conditions. A novel H7N9 immune escape virus has emerged. Faced with potential outbreaks, we should strengthen surveillance and update vaccine strains.
Community supported agriculture (CSA) serves as a platform for local producers, especially for small size farms, to sell fresh, local products directly to its members. CSA is an important approach to promote local economic growth and contribute to sustainable agriculture. Although CSA is widely accepted across the United States, the total number of CSA membership is still very low. It is important to determine the factors that affect the future development of CSA because of its social and environmental benefits. In this study, we analyze how the motivation, barriers, and methods of advertisement influence the participation dynamics of CSA by segmenting consumers based on their past, current, and future CSA participation. Based on a national survey with 795 responses, the results show that the younger generation, high-income families, and people who support sustainable agriculture are more likely to renew their CSA subscription. CSA members are found to be very sensitive to the time of food distribution, the price of products, and the location of CSA farms. Moreover, the impacts of perceived barriers of CSA participation and advertisement method vary based on respondents’ membership status. This paper sheds light on factors that influence various consumer groups and offers a more dynamic analysis of CSA consumer behavior. This analysis enhances understanding of CSA members’ preferences and could help CSA programs expand in the future and to better promote local food systems and sustainable agriculture.
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