A magnetic bimeron is an in-plane topological counterpart of a magnetic skyrmion. Despite the topological equivalence, their statics and dynamics could be distinct, making them attractive from the perspectives of both physics and spintronic applications. In this work, we demonstrate the stabilization of bimeron solitons and clusters in the antiferromagnetic (AFM) thin film with interfacial Dzyaloshinskii–Moriya interaction (DMI). Bimerons demonstrate high current-driven mobility as generic AFM solitons, while featuring anisotropic and relativistic dynamics excited by currents with in-plane and out-of-plane polarizations, respectively. Moreover, these spin textures can absorb other bimeron solitons or clusters along the translational direction to acquire a wide range of Néel topological numbers. The clustering involves the rearrangement of topological structures, and gives rise to remarkable changes in static and dynamical properties. The merits of AFM bimeron clusters reveal a potential path to unify multibit data creation, transmission, storage, and even topology-based computation within the same material system, and may stimulate spintronic devices enabling innovative paradigms of data manipulations.

PlacketteBurman designBoxeBehnken design Naproxen Quality by design a b s t r a c tThe study aims to prepare naproxen enteric-coated pellets (NAP-ECPs) by fluid-bed coating using QbD principle. Risk assessment was firstly performed by using failure mode and effect analysis (FMEA) methodology. A PlacketteBurman design was then used for assessment of the most important variables affecting enteric-coated pellets characteristics. A BoxeBehnken design was subsequently used for investigating the main, interactive, and quadratic effects of these variables on the response. By FMEA we discovered that eight factors should be considered to be high/important risk variables as compared with others.The responses of acid resistance and cumulative drug release were taken as critical quality attributes (CQAs). Pareto ranking analyses indicated that the coating weight gain (X 7 ), triethyl citrate percentage (X 1 ) and glycerol monostearate percentage (X 2 ) were the most significant factors affecting the selected responses out of the eight high-risk variables.Optimization with response surface method (RSM) further fully clarified the relationship between X 7 , X 1 , X 2 and CQAs, and design space was established based on the constraints set on the responses. Due to the extreme coincidence of the predicted value generated by model with the observed value, the accuracy and robustness of the model were confirmed.It could be concluded that a promising NAP-ECPs was successfully designed using QbD approach in a laboratory scale.

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The magnetic skyrmionium can be seen as a coalition of two magnetic skyrmions with opposite topological charges and has potential applications in next-generation spintronic devices. Here, we report the current-driven dynamics of a skyrmionium in a ferromagnetic nanotrack with the voltage-controlled magnetic anisotropy. The pinning and depinning of a skyrmionium controlled by the voltage gate are investigated. The current-driven skyrmionium can be used to mimic the skyrmionium diode effect in the nanotrack with a voltage gate. We have further studied the skyrmionium dynamics in the nanotrack driven by a magnetic anisotropy gradient in the absence of spin current. The performance of a single wedge-shaped voltage gate at different temperatures is studied. Our results may provide useful guidelines for the design of voltage-controlled and skyrmionium-based spintronic devices.