Multifunctional "smart" particles with magnetic, topographic, cell-targeting, and stimulus-responsive properties are obtained using a "live template" strategy. These particles exhibit improved efficiency in capture of target cancer cells by introducing synergistic topographic interactions, and enable the release of captured cells with high viability via reduction of disulfide bonds. Diverse multifunctional particles can be designed using the "live template" strategy.

Nd:LuAG (Nd:Lu 3 Al 5 O 12 ) crystal was grown by the Czochralski method. X-ray powder diffraction experiments show that the Nd:LuAG crystal crystallizes in the cubic with space group Ia3d and has the cell parameter: a = 1.1907 nm, V = 1.6882 nm 3 . The absorption and fluorescence spectra of Nd:LuAG crystal at room temperature were investigated. With a fiber-coupled diode laser as pump source, the continuous-wave (CW) laser action of Nd:LuAG crystal was demonstrated. The maximum output power at 1064 nm was obtained to be 3.8 W under the incident pump power of 17.3 W, with the optical conversion efficiency 22.0% and the slope efficiency 25.7%.Output power, W

The continuous wave (CW) and passively Q-switched performances of Nd:CaYAlO(4) crystal with both a- and c-cut were demonstrated. The CW output powers of 1.15 W and 1.26 W were obtained under the pump power of 8.96 W with slope efficiencies of 15.2% and 16.8% for a- and c-cut samples, respectively. As a result, new dual-wavelength all-solid-state lasers at 1080 nm and 1081 nm were achieved with c-cut crystal. By using Cr(4+):YAG wafer as saturable absorber, we performed Q-switching experiments. The highest average output powers and shortest pulse widths were measured to be 0.798 W, 10.6 ns and 0.537 W, 9.6 ns for a- and c-cut samples, respectively.