Objective. Previous studies have yielded conflicting results regarding the association of coronavirus disease 2019 (COVID-19) with allergic rhinitis (AR). Data on AR prevalence in COVID-19 patients are limited. Consequently, whether AR is a harmful or protective factor for COVID-19 patients remains controversial. Therefore, we analyzed the relationship between COVID-19 and AR. Methods. We systematically searched PubMed, Embase, Cochrane, and Web of Science databases for studies published between January 1, 2020 and January 11, 2022. We included studies reporting the epidemiological and clinical characteristics of COVID-19 and its incidence in patients with AR. We excluded letters, case reports, literature review articles, non-English language article, and non-full-text articles. The raw data from these studies were pooled into a meta-analysis. Results. We analyzed the results of nine studies. The prevalence of AR in patients with COVID-19 was 0.13 (95% confidence interval [CI] 0.04–0.25), with an overall I2 of 99.77%, P = 0.24 . COVID-19 patients with AR are less prone to severe disease (odds ratio [OR] = 0.79, 95% CI, 0.52–1.18, P = 0.25 ) and hospitalization (OR = 0.23, 95%CI, 0.02–2.67, P ≤ 0.0001 ) than patients without AR. Conclusion. Our data suggest that allergic rhinitis is a protective factor in patients with COVID-19.

Multiorgan-penetrating injuries to the head and neck are relatively uncommon, with many complications and high mortality, and the management of such injuries is often complex and nonstandardized. Here, we report our experience of treating such injuries. We retrospectively analyzed multiorgan-penetrating injuries to the head and neck in patients who were admitted to and managed in our department. We evaluated first-aid measures, imaging examination findings, operation method, and prognoses. A total of 5 patients were identified. The patients were successfully treated; two of these patients with wooden foreign bodies underwent digital subtraction angiography (DSA) of the common carotid artery. To sum up, we conclude that individualized multidisciplinary treatment according to the affected organs and manner of impalement can greatly reduce intraoperative and postoperative complications. In endoscopy-assisted removal with irregular wooden foreign bodies, we advocate intraoperative DSA of common carotid arteries as a routine procedure.

Rosai-Dorfman disease (RDD), also known as sinus histiocytosis with massive lymphadenopathy, is an uncommon histiocytic disease with idiopathic etiology and unique pathology. Extra-nodal RDD that occurs in the nasal cavity is extremely unusual and the characteristic clinical features are unknown. Herein, we report a case of nasal septum RDD, with intermittent epistaxis from the left nasal cavity, which led to collapse of the nasal bridge. The patient underwent surgical biopsy, and a diagnosis of nasal septum RDD was established. No further treatment was performed. An enlarged mass was found in the second postoperative year which was treated by surgical excision in the third postoperative year. To improve the current diagnostic and therapeutic approach of extra-nodal RDD, we incorporate previous reports from the literature to discuss the pathological characteristics, pathogenesis, clinical manifestations, diagnosis, and therapy for this rare disease.