Objective This study aims to investigate the diagnostic value of three-dimensional pelvic ultrasound in the preoperative assessment of anal fistula compared with findings of MRI and surgery. Methods A total of 67 patients (62 males) with suspected anal fistula were analyzed retrospectively. Preoperative three-dimensional pelvic ultrasound and magnetic resonance imaging were performed in all patients. The number of internal openings and the type of fistula were recorded. The accuracy of three-dimensional pelvic ultrasound was determined by comparing these parameters with surgical outcomes. Results At surgery, 5 (6%) were extrasphincteric, 10 (12%) were suprasphincteric, 11 (14%) were intersphincteric, and 55 (68%) were transsphincteric. There was no significant difference in the accuracy of pelvic 3D US and MRI, based on internal openings (97.92%, 94.79%), anal fistulas (97.01%, 94.03%), and those under Parks classification (97.53%, 93.83%). Conclusion Three-dimensional pelvic ultrasound is a reproducible and accurate method for determining the type of fistula and detecting internal openings and anal fistulas.
Objective In this study, we investigated the diagnostic value of pelvic floor three-dimensional ultrasound for anal fistula. Methods Sixty-seven patients (62 males) with anal fistula were included in the study. All patients underwent pelvic floor three-dimensional ultrasound and magnetic resonance imaging before the operation.. The type of fistula and the number of internal openings were documented. These parameters were compared with the postoperative outcomes. Results At surgery, 11(14%) were intersphincteric, 55(68%) transsphincteric, 10(12%) suprasphincteric and 5(6%) extrasphincteric. There were no significant differences(P > 0.05) in the accuracy rates of pelvic three-dimensional ultrasound and MRI, in terms of anal fistulas (97.01%, 94.03%), internal openings (97.92%, 94.79%) and those under Parks classification (97.53%, 93.83%). Conclusion Three-dimensional pelvic floor ultrasound is an accurate and reproducible method for detecting anal fistulas and internal openings, as well as determining the type of fistula.
Background: Viral pneumonia has always been a problem faced by clinicians because of its insidious onset, strong infectivity and lack of effective drugs. Patients with advanced age or underlying diseases may experience more severe symptoms and are prone to severe ventilation dysfunction. Reducing pulmonary inflammation and improving clinical symptoms is the focus of current treatment. Low-intensity pulsed ultrasound (LIPUS) can mitigate inflammation and inhibit edema formation. We aimed to investigate the effectiveness of therapeutic LIPUS in improving lung inflammation in hospitalized patients with viral pneumonia. Methods: This study protocol entails a prospective, randomized controlled trial. 60 eligible participants with clinically confirmed viral pneumoniawill be assigned to either (1) test group (LIPUS stimulus), (2) external control group (null stimulus), or (3) self-control group (LIPUS stimulated areas versus non-stimulated areas). The primary outcome will be the difference in the extent of absorption and dissipation of lung inflammation on computed tomography andultrasonography images. Secondary outcomes include pulmonary function, blood gas analysis, fingertip arterial oxygen saturation, serum inflammatory factor levels, the sputum excretion volume, time to the disappearance of pulmonary rales, pneumonia status score, and course of pneumonia. Adverse events will be recorded. Intention-to-treat analyses will be used. Discussion: This study is the first clinical study of the effectiveness of therapeutic LIPUS in the treatment of viral pneumonia. Given that the current clinical recovery mainly depends on the body's self-limiting and conventional symptomatic treatment, LIPUS, as a new therapy method, might be a major advance in the treatment of viral pneumonia. Trial registration: ChiCTR2200059550 Chinese Clinical Trial Registry
Background Viral pneumonia has always been a problem faced by clinicians because of its insidious onset, strong infectivity, and lack of effective drugs. Patients with advanced age or underlying diseases may experience more severe symptoms and are prone to severe ventilation dysfunction. Reducing pulmonary inflammation and improving clinical symptoms is the focus of current treatment. Low-intensity pulsed ultrasound (LIPUS) can mitigate inflammation and inhibit edema formation. We aimed to investigate the efficacy of therapeutic LIPUS in improving lung inflammation in hospitalized patients with viral pneumonia. Methods Sixty eligible participants with clinically confirmed viral pneumonia will be assigned to either (1) intervention group (LIPUS stimulus), (2) control group (null stimulus), or (3) self-control group (LIPUS stimulated areas versus non-stimulated areas). The primary outcome will be the difference in the extent of absorption and dissipation of lung inflammation on computed tomography. Secondary outcomes include changes in lung inflammation on ultrasonography images, pulmonary function, blood gas analysis, fingertip arterial oxygen saturation, serum inflammatory factor levels, the sputum excretion volume, time to the disappearance of pulmonary rales, pneumonia status score, and course of pneumonia. Adverse events will be recorded. Discussion This study is the first clinical study of the efficacy of therapeutic LIPUS in the treatment of viral pneumonia. Given that the current clinical recovery mainly depends on the body’s self-limiting and conventional symptomatic treatment, LIPUS, as a new therapy method, might be a major advance in the treatment of viral pneumonia. Trial registration ChiCTR2200059550 Chinese Clinical Trial Registry, May 3, 2022.
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