BACKGROUND: Physicians frequently prescribe antibiotics to inpatients without knowledge of medication cost. It is not well understood whether providing cost data would change prescribing behavior. OBJECTIVE: To evaluate the association between providing cost data alongside culture and antibiotic susceptibility results and prescribing of high-cost antibiotics. DESIGN: Quasi-experimental pre-post analysis. PARTICIPANTS: Inpatients diagnosed with bacteremia or urinary tract infection in two tertiary care hospitals. INTERVENTION: Cost category data for each antibiotic ($, $$, $$$, or $$$$) were added to culture and susceptibility testing results available to physicians. MAIN MEASURES: Average cost category of antibiotics prescribed to patients after the receipt of susceptibility testing results. KEY RESULTS: There was a significant decrease in the average cost category of antibiotics per patient after the intervention (pre-intervention = 1.9 $ vs. postintervention = 1.7 $, where 1.5 $ would mean that the average number of dollar signs for antibiotics prescribed was between $ and $$, p=0.002). After adjusting for age, insurance type, and prior length of stay, the odds ratio (OR) of a patient's average antibiotic being higher cost vs. lower cost after the intervention compared to before the intervention was 0.74 [95 % confidence interval (CI) 0.56, 0.98]. The intervention was associated with a 31.3 % reduction in the average cost per unit of antibiotics prescribed (p<0.001). CONCLUSIONS: Providing physicians with cost feedback alongside susceptibility testing data was associated with a significant decrease in prescription of high-cost antibiotics. This intervention is intuitive, low cost, and may shift providers toward lower cost medications when equally acceptable options are available.KEY WORDS: infectious disease; hospital medicine; health care costs, medical decision making.

No abstract