Study Design-Prospective Observational CohortsObjective-To describe sociodemographic and clinical features, and non-operative (medical) resource utilization prior to enrollment, in patients who are candidates for surgical intervention for intervertebral disc herniation (IDH), spinal stenosis (SpS), and degenerative spondylolisthesis (DS) according to SPORT criteria. Summary of Background Data-Intervertebral disc herniation, spinal stenosis, and degenerative spondylolisthesis with stenosis are the three most common diagnoses of low back and leg symptoms for which surgery is performed. There is a paucity of descriptive literature examining large patient cohorts for the relationships among baseline characteristics and medical resource utilization with these three diagnoses. Conclusion-IDH patients appear to have differences in sociodemographics, resource utilization, and functional impairment when compared to the SpS/DS patients. In addition, the differences in resource utilization for Medicaid patients may reflect differences in access to care. The data provided from these observational cohorts will serve as an important comparison to the SPORT randomized cohorts in the future. Methods-The

When revision due to either infection or aseptic loosening is considered to be the primary outcome, the use of antibiotic-impregnated bone cement results in an overall cost decrease. When only revision due to infection is considered, the model is strongly influenced by the cost of the cement and the average age of the patients. With few patients less than seventy years of age undergoing total hip arthroplasty with cement in the United States, the use of antibiotic-impregnated bone cement in primary total hip arthroplasty may be of limited value unless its cost is substantially reduced.

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