Primary malignant melanoma of the central nervous system is rare, and the events involving the spinal cord are even more infrequent. A 30-year-old male presented with a mass lesion of the spinal cord. After radiological workup, the mass was resected in December 2012. The histopathological examination report and immunohistochemistry suggested malignant melanoma. PET-CT scan, brain MRI, and funduscopic examination did not reveal malignant melanoma elsewhere in the body. The patient received postoperative radiotherapy until March 2013. Presently, the patient is asymptomatic with normal neurological functions.

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Solid organ transplant recipients are at increased risk of developing malignancies, even decades after transplant, due to the prolonged use of immunosuppressant drugs. A 35-year-old male underwent renal transplant for end stage renal disease 18 years previously and was on immunosuppressive drugs since that time and was on regular follow up. In 2016, he developed a squamous cell carcinoma of tongue, which was operated and adjuvant radiation therapy was given. The patient is currently on follow up and asymptomatic. Though squamous cell carcinoma of tongue is a relatively common malignancy in the general population, it is very rare in transplant recipients. Hence, such patients require longer follow-up, active surveillance, and screening for early diagnosis and prompt treatment of premalignant and malignant conditions. Key words:Renal transplant, immunosuppression, carcinoma tongue ABSTRACTArticle history: