No abstract

Background: Phenolic constituents of plant are the prime source of antioxidants. Natural antioxidant biomolecules become an emerging research area of this era because of their antioxidant potential. Accumulation of free radicals results in occurrence of many degenerative diseases and produced harmful effect on body. Research evidence proved that plant phenolic constituents have an antioxidant potential and has been used for the treatment of degenerative diseases. Therefore, an attempt was taken to investigate the antioxidant activity and total phenolic content of Sida cardifolia, Abutilon indicum and Mesua ferrea. Materials and Methods: Alcoholic, hydroalcoholic and water extracts of S. cardifolia, A. indicum and M. ferrea were prepared and total phenolic content was determined by Folin Ciocalteu method, and antioxidant activity was determined by DPPH free radical scavenging method. Results: Poly phenolic Result revealed that hydroalcoholic extracts of S. cardifolia, A. indicum and M. ferrea showed maximum phenolic content than the alcoholic and water extracts. In vitro Antioxidant study revealed that hydroalcoholic extract of S. cardifolia and M. ferrea showed optimum antioxidant activity while aqueous extract of A. indicum showed maximum antioxidant activity. Conclusion: Aqueous extract of A. indicum showed maximum antioxidant activity than hydroalcoholic extract of S. cardifolia and M. ferrea.

Excess of Free radicals leads to accumulation in body which results in oxidative stress. Accumulation of free radicals results in diseases like cancer, arthritis, skin diseases, autoimmune disorders, aging, cataract, rheumatoid arthritis, cardiovascular and neurodegenerative diseases. Antioxidants play crucial role in the management of such diseases. Polyphenolic constituents of plants are the good source of antioxidant, can be use in the treatment and management of many diseases. The aim of present study invitro evaluation of antioxidant and photoprotective activity of the alcoholic, hydroalcoholic and aquous extracts of S. cardifolia and A. indicum. Aquous, hydroalcholic and alcoholic extract of S. cardifolia and A. indicum were prepared and evaluated for total phenolic content by Folin-ciocaltechu method, antioxidant activity by DPPH method and photoprotective effect by UV spectrophotometer method. Results showed that hydroalcoholic extracts of S. cardifolia and A. indicum showed highest phenolic content, while hydroalcoholic extract of S. cardifolia and water extract of A. indicum showed potent antioxidant activity, while hydroalcoholic extract of S. cardifolia and A. indicum showed maximum photoprotective effect as compared to alcoholic and water extract. Hydroalcoholic extracts of S. cardifolia and A. indicum showed highest phenolic content, potent antioxidant activity and maximum photoprotective effect. The result revealed that S. cardifolia and A. indicum possess potent antioxidant and photoprotectve effect, which can be use in the management of various diseases and as a photo protective in skin diseases.