We report a 2-year-old girl suffering from acute liver failure as a result of paracetamol poisoning. The child successfully recovered after intensive care. We performed literature search for the past decade and found that the pathophysiological response in the child was different from that of the adult. Despite paracetamol poisoning being one of the most common poisonings in the world, there is still no consensus in the treatment protocol. Hence the role of the Hong Kong Poison Information Centre is briefly discussed.

A 68-year-old lady attended the clinic early this year for bilateral upper and lower limb oedema for about two weeks. Apart from hypercholesterolemia, she otherwise had enjoyed good past health. Recently she was disturbed by swelling in all four limbs in the past two weeks. The swelling was mainly located in the hands, fingers and ankles which was affecting her movement. The symptom was associated with general malaise, weakness and mild breathlessness on exertion. She felt that she was "heavier" than before, despite there being no objective weight gain. There was no orthopnoea or paroxysmal nocturnal dyspnoea. Neither nocturia nor frothy urine was found. No systemic upset was noted and her appetite was good. The general examination revealed that the oedema was located as mentioned. Systemic examinations did not show any particular alarming feature. Cardiovascular, thyroid status, respiratory, abdominal and neurological examinations were all unremarkable. Her blood

An elite runner presented with macroscopic haematuria after six hours of non-stop running during his training for Trailwalker. The haematuria resolved after two days of conservative treatment. The history, pathophysiology and complication of runner-related haematuria are discussed. A simplified management plan is suggested in order to avoid unnecessary anxiety to the patients, inappropriate referral and wasting of medical resources.

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