Summary. For the treatment of breast cancer the modified radical mastectomy is the most widely used operation. We have altered the original technique in some respects: the protuberation of the breast is circumcised horizontally. Then 3-to 4-mm-thick skin flaps are dissected down to the rectus muscle, to the midline of the sternum, up to the clavicle, and to the edge of the latissimus dorsi muscle laterally. The breast, together with the pectoralis fascia, is then dissected from the pectoralis major muscle. The pectoralis minor muscle is transected near its insertion but left in place, which provides adequate access for the dissection of the axilla. A local recurrence rate of 5.4% justifies the meticulous preparation.Key words: Modified radical mastectomy -Technique. Zusammenfassung. Zur Behandlung des Brustkrebses hat sich die modifiziert radikale Mastcktomieetabliert. Wir haben die Originalmethode abge~tndert: Die Protuberation der Brust wird quer oval~ir umschnitten. Sodann werden die Hautr~nder bis zum Ansatz des Musculus rectus abdominis, bis Sternummitte, his zum unteren Rand der Clavicula sowie bis zum ~iuBeren Rand des Musculus latissimus dorsi in einer Dicke yon 3-4 mm unterminiert. Die BrustdrOse wird dann yon medial her mitsamt der Pectoralis-Fascie abpr~tpariert. Der Musculus pectoralis minor wird ansatznahe durchtrennt, jedoch belassen, wodurch ein ausreichender Zugang for die Dissektion der Axilla geschaffen wird, Eine Lokalrezidivquote von nut 5,4% rechtfertigt die aufwendige Preparation. Schliisseiwi)rter:Modifiziert radikale Mastektomie -Technik.

No abstract

No abstract

The various groups who are working on islet-transplantation used different parameters in determining the success or failure of their experiments. In our own transplantation-trials we tested the value of using the symptoms typical of diabetic humans for rats. These are: change in bodyweight, water intake, urine-volume and glucose content as well as the glucose-level in the blood. Special diabetic provocation-tests were also carried out with rats. It was shown, that the i.v. glucose-tolerance-test (IVGTT) and the glucose assimilation-coefficient (GAC) were able to demonstrate the reversal of the diabetic state after islet-transplantation. The tolbutamid-test gave no additional evidence about the success of the transplantation. Histological examinations should always be carried out in addition to the biochemical tests, because a decrease in the islet's-function is shown to depend on a higher rate of morphological regressions.

No abstract