The phenomenon of fibrinolysis in thromboembolic disease is of great importance. In this communication the authors present striking evidence of fibrinolysis induced by drugs.

Response of peripheral blood flow was studied in subjects of various age groups with and without vascular disease. Under constant environmental conditions, the skin-muscle distribution of total flow to the lower extremity showed the following trend. In young healthy adults the muscles get a somewhat higher share; in elderly persons without vascular disease the distribution is about equal; in patients with nongangrenous obliterative arteriosclerosis the skin is favored over the muscle. Exercise increases total flow in all groups, but does not alter the distribution. Sympathectomy does not seem to influence response to exercise.

No abstract