Trisalkylpyridiniurn porphyrins substituted by one glycosyl (glucosyl, maltosyl, and lactosyl) moiety have been prepared in acceptable yields. These glycosylated cationic porphyrins have been synthesized from pyrrole condensed with 4-pyridinecarboxaldehyde, and suitable ortho-orpara peracetylglycosyloxybenzaldehyde derivatives in refluxing propionic acid -Ac20 followed by action of alkyliodide in DMF. Deprotection of the glycosylated moieties led to a new class of representative glycosylated porphyrins.Key words: porphyrins, cationic, glycosylated; phototherapy, cancer.RCsumk : On a prCparC des tris(alky1pyridiniurn)porphyrines substituCes par une portion glycosyle (glucosyle, maltosyle et lactosyle) avec des rendements acceptables. On a synthttist ces porphyrines cationiques glycosylCes a partir de pyrrole condens6 avec un pyridine-4-carboxyaldChyde et des derives ortho-ou para-peracCtylglycosyloxybenzaldChydes approprits, par reflux dans de l'acide propanoi'que -Ac20, suivi par l'action d'un iodure d'alkyle dans le DMF. La dkprotection des portions glycosylCes conduit a une nouvelle classe de porphyrines glycosyltes representatives.
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