Highlights► Previously we showed that CGRP can increase ectopic discharge at nerve injury sites. ► Here we monitor the effect of anti-CGRP antibody on injured nerve fibre activity. ► Systemic anti-CGRP does not modify activity in injured lingual nerve fibres. ► Activity in injured lingual nerve fibres is not affected by sequestration of CGRP. ► Other modulators may offer better therapeutic targets for nerve injury-induced pain.
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