A migraine is the most common cause of severe, recurring headache. With the recent advances in our understanding of migraine, it can be effectively treated and even prevented. Prophylactic treatment of migraines is indicated when patients have three or more severe migraine attacks a month that interfere with quality of life or when attacks are prolonged and symptomatic medication used alone is not satisfactory. The major objective of migraine prophylactic therapy is optimizing the patient's ability to function normally by reducing the frequency, duration, and intensity of attacks. The major migraine preventive therapies include β-blockers, calcium-channel blockers, and tricyclic medications. Preventive treatment should be tailored to individual patient needs. This requires that patient and healthcare professionals understand the rationale and participate actively in decisions regarding therapeutic intervention.

Atherosclerosis of large and medium sized arteries are believed to be the major reason behind the development of Coronary Artery Diseases and Hyperlipidemia has been found to be one of the most important contributing factors. Appropriate lifestyle changes along with proper drug therapy lead to a considerable reduction in mortality rate due to coronary artery disease. Reduction of LDL Cholesterol is the primary goal of cholesterol-lowering therapy, but most of the patients are usually unable to achieve the treatment goals with lifestyle modifications alone; and in such situations, drug therapy is essential to prevent the disease progression and further future complications. The aim of the study was to demonstrate impact of three moderate intensity statins on lipid profile and biomarker representing muscle toxicity. It was a prospective observational study conducted in a tertiary care teaching hospital in south India. Patients of both gender falling the age group between 30 and 70 years with newly diagnosed Hyperlipidemia attending the Department of Medicine OPD, were enrolled in the study. Total 229 participants were enrolled in study and all the drug treatment were found to be effective in achieving the treatment goal; at the same time Rosuvastatin 10 mg treatment group exhibited better efficacy along with minimal muscle toxicity.

This study was aimed to analyses the serum Hs-CRP level and fasting Blood Sugar level in patients with Hyperlipidemia in a Super Specialty Teaching Hospital in north Kerala. This was a hospital-based prospective observational study which was conducted to study the status of Hs-CRP and Fasting Blood sugar level on lipid profile status of newly diagnosed Hyperlipidemia patients which was compared with Normal Lipid Profile people. Healthy subjects were recruited as a control group and newly Diagnosed Hyperlipidemia patients were recruited as Test group. Study subjects of both gender in an age group of 30 to 70 were selected for the study. Serum Hs CRP, Fasting Blood sugar and serum lipid profile were estimated after overnight fasting condition. After the biochemical estimation, values were entered in an Excel sheet and level of test and control group was statistically analyzed by using Student's t-test using SPSS software. The values were expressed in Mean ± Standard Deviation (SD) and The status of serum Hs CRP, fasting Blood Sugar and Lipid Profile Parameters were shown a statistically significant difference (p<0.01) between Control and Test groups. The result of the study points out that the elevated level serum Hs-CRP and Fasting Blood Sugar can be used as predictive markers of Hyperlipidemia.

Epidemiological study is a simple, reliable method for quantifying body size and proportions. This study was aimed to evaluate the association of selected & established demographic parameters of patients with Hyperlipidemia in a rural hospital set up. This study was a hospital-based cross sectional study conducted in patients with newly diagnosed Hyperlipidemia in an age group of 30 to 70 years attending Cardiology Department of a tertiary care hospital in south India. Based on the lipid profile, the subjects were grouped into Normal and Test groups and demographic data and serum lipid profile were recorded in previously designed Data Collection form and statistically analyzed. The result from this study shows that the body weight, height, Body Mass Index and waist circumference of the test population were significantly higher than that of the control population. Also Fasting Blood sugar level, Systolic BP and Diastolic BP were found to be significantly higher in Test group when it compares with the control group. Based on the result from this study, we shall conclude that Body Mass Index, Waist Circumference, Fasting Blood Sugar, and Blood Pressure are very sensitive indices for predicting the elevated biomarkers of Hyperlipidemia.

GDM is a condition in which high blood glucose level is exhibited in a women during pregnancy without a previous diagnosis of Diabetes Mellitus. Indian women are considered to be more prone for developing GDM. The increasing prevalence of GDM may be due to obesity, family history of Diabetes Mellitus, sedentary lifestyle, genetic predisposition and dietary habits. The screening and management of GDM in the general population remain controversial with conflicting guidelines and treatment protocols. Adequate blood sugar control in GDM women might reduce various maternal, foetal and neonatal complications. Prospective Observational study was done to find out the prevalence and risk factors of GDM. The study was conducted in the OBG department of the study center and pregnant women with 24-28 weeks of gestation attending for antenatal care were included. The results obtained from the study says the prevalence of GDM was found to be 16% in the study center, which is at par with South Indian prevalence. This study concludes that GDM is largely associated with a family history of diabetes mellitus, obesity and higher maternal age in that particular study setup.