The Posterior Reversible Encephalopathy Syndrome (PRES) is an acute clinical condition that is characterized by multiple neurological symptoms such as seizures, impairment of consciousness, headaches, visual abnormalities, nausea, and vomiting. The characteristic imaging finding is vasogenic oedema predominantly in the parieto-occipital white matter of the brain. Delaying seizure control, refractory status epilepticus, and malignant PRES carry high morbidity and mortality. We report a case of Sri Lankan girl with nephrotic syndrome developing status epilepticus due to PRES.