It has been found that higher alkyl sulfate (C 10-48) of several basic chemicals such as thiamine form complexes comparatively easily with cyclodextrin, especially a-dextrin in water or hydrated ethanol solution. The complexes contain about 100 of alkyl sulfate which was extracted by 90% ethanol at room temperature.A comparison of X-ray diffraction patterns by the powder method showed that these complexes have a resembling crystalline structure with the cyclodetrin complexes already known and it was concluded to be inclusion compounds having constant molar ratio.It was also observed that the thiamin dilauryl sulfate among a-and ~-cyclodextrin complexes provided pretty higher stabilities against alkali under high temperature and high humidity.Water soluble chemicals which are usually difficultly included, will form inclusion compound when it will be transf eyed to alkyl sulfate.
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