Sepsis is the most frequent cause of mortality in patients with acute illness worldwide [1]. Delays in the identification of sepsis and its management often result in rapid deterioration to circulatory collapse, multiple organ failure, and eventually death [2]. Therefore, prompt diagnosis of sepsis and rapid initiation of treatment can positively impact patient outcomes and reduce costs [3,4]. Sepsis is defined as a dysregulated immune response to an infectious insult, which results in life-threatening organ dysfunction [5].A positive microbiological culture is an accepted benchmark for distinguishing sepsis from noninfectious conditions. However, bacteria may take a long time to grow, and during this phase, the condition of the patients may promptly decline. To date, no single ideal biomarker for sepsis has been identified [6]. Thus, there is an urgent need for a biomarker that can identify sepsis in an early stage as
Background: This study was designed to compare the lipid profile among prehypertensive and normotensive and its correlation between blood pressure and lipid profile in prehypertensive patients. Methods: This case-control study on forty prehypertensives and forty normotensive subjects. Blood pressures were recorded and serum lipid profiles were measured and compared using student t test. Correlation between blood pressure and serum lipid profile was done. Results: The mean SBPs of prehypertensives group and normotensives group were 132.43±6.25 mmHg versus 110.02±2.60 mmHg, respectively, and mean DBPs were 88.42±4.05 mmHg versus 74.21±3.72 mmHg, respectively. The mean SBP and DBP of prehypertensives group were higher than those of normotensives group. the serum lipid profile of recently, diagnosed prehypertensive patients was significantly altered as compared to normotensive subjects. Conclusion: The serum lipid profile of recently, diagnosed prehypertensive patients was significantly altered as compared to normotensive subjects.
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