In a study involving 10 different sites, independent results of measurements of ultrasonic properties on equivalent tissue-mimicking samples are reported and compared. The properties measured were propagation speed, attenuation coefficients, and backscatter coefficients. Reasonably good agreement exists for attenuation coefficients, but less satisfactory results were found for propagation speeds. As anticipated, agreement was not impressive in the case of backscatter coefficients. Results for four sites agreed rather well in both absolute values and frequency dependence, and results from other sites were lower by as much as an order of magnitude. The study is valuable for laboratories doing quantitative studies. KEY WORDS: Measurements; Speed; Attenuation; Backscatter; Interlaboratory comparison. n 1986 an article was published to compare measurements made of ultrasonic attenuation coefficients and propagation speeds in TM phantom materials produced at the University of Wisconsin and sent to participating laboratories. 1 To assess stability of ultrasonic properties during the study, measurements were done on those phantoms at the University of Wisconsin laboratories before and after the measurements were made at other laboratories. The same type of study, involving 10 labo-
Integration of ferroelectric materials into nanoscale field-effect transistors offers enormous promise for superior transistor performance and also intriguing memory effects. In this study, we have incorporated lead zirconate titanate (PZT) into In2O3 nanowire transistors to replace the commonly used SiO2 as the gate dielectric. These transistors exhibited substantially enhanced performance as a result of the high dielectric constant of PZT, as revealed by a 30-fold increase in the transconductance and a 10-fold reduction in the subthreshold swing when compared to similar SiO2-gated devices. Furthermore, memory effects were observed with our devices, as characterized by a counter-clockwise loop in current-versus-gate-bias curves that can be attributed to the switchable remnant polarization of PZT. Our method can be easily generalized to other nanomaterials systems and may prove to be a viable way to obtain nanoscale memories.
Similar to optical tweezers, a tightly focused ultrasound microbeam is needed to manipulate microparticles in acoustic tweezers. The development of highly sensitive ultrahigh frequency ultrasonic transducers is crucial for trapping particles or cells with a size of a few microns. As an extra lens would cause excessive attenuation at ultrahigh frequencies, two types of 200-MHz lensless transducer design were developed as an ultrasound microbeam device for acoustic tweezers application. Lithium niobate single crystal press-focused (PF) transducer and zinc oxide self-focused transducer were designed, fabricated and characterized. Tightly focused acoustic beams produced by these transducers were shown to be capable of manipulating single microspheres as small as 5 μm two-dimensionally within a range of hundreds of micrometers in distilled water. The size of the trapped microspheres is the smallest ever reported in the literature of acoustic PF devices. These results suggest that these lensless ultrahigh frequency ultrasonic transducers are capable of manipulating particles at the cellular level and that acoustic tweezers may be a useful tool to manipulate a single cell or molecule for a wide range of biomedical applications.
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