Introduction: Birth weight (BWT) is greatly affected by placental insufficiency and the microvessels configurations. Aims of this study were to evaluate various parameters: villous density (VD), microvessel density (MVD), microvessels per villus (MVPV), mean microvessel caliber (VC), total microvessels boundary density (TVBD), maximum possible total length of microvessels (MP-TVL) and maximum possible total surface area of microvessels (MP-TVSA) in terminal villi of placenta. All the parameters including placental weight (PWT) were correlated with BWT; and MVD and VC of placenta were compared with the human tissues from various lesions. Materials and methods:Sixty human placentas of uncomplicated term pregnancies (≥37weeks) managed at this tertiary care institute were included. Formalin fixed paraffin embedded sections of placental tissues were used for computer assisted digital image morphometry. H&E stained sections were used to determine VD and CD34 immuno-stained sections were used for evaluation of vascular parameters in terminal villi. Results: The mean VD was 204 mm-2, the mean MVD was 1314 mm-2, the mean MVPV was 6.6, the mean MVC was 10.15 µm, the mean TVBD was 40.64 mm-1, the mean MP-TVL was 626 km and the mean MP-TVSA was 19.23 m2. The BWT showed significant (p<0.05) positive correlations with PWT (r=0.690), VD (r=0.328), MVD (r=0.408), TVBD (r=0.280), MP-TVL (r=0.723) and MP-TVSA (r=0.723); whereas did not show significant correlations with MVPV (r=0.185, p=0.157) and VC (r=-0.249, p=0.054). MVD in placentas showed strong negative correlation with VC (r=-0.712). MVD in placentas were several times (~ 6.3 times) higher than human tissues; though mean caliber of microvessels in placenta was comparable. Conclusion:PWT, VD, MVD and TVBD in placenta showed significant positive correlations with BWT. Estimated MP-TVL and MP-TSA showed the best correlations with BWT. Placental MVD showed strong negative correlation with VC. Total length of microvessels in the placenta was comparable to that estimated for the fetus. Keywords: Microvessels in

Study of AMH levels of patients of ART Centre and its variations has clinical relevance in the field of assisted reproductive technology. Diminished ovarian reserve has become a major cause of infertility. Anti-Mullerian hormone (AMH) seems to be a promising candidate to assess ovarian reserve and predict the response to controlled ovarian hyperstimulation (COH).  The study is a prospective, observational study carried in Department of Anatomy in collaboration with Assisted Reproductive Technology centre at a tertiary care teaching hospital. The study is carried out on eighty females who had reported to ART centre for treatment for the first time, because of involuntary childlessness with at least 1 year of unprotected intercourse without pregnancy.  In our study, eighty females were divided into four groups depending upon their AMH levels. The number of oocytes collected from each female on the day of oocyte pickup was documented. Comparison with previous studies was done. Knowledge of AMH levels will help gynaecologist to counsel the infertility patient prior to initiation of the IVF cycle. It not only allows the quantification of ovarian reserve but also predict the eventual ovarian response to ovarian stimulation and the clinical pregnancy. Keywords: AntiMullerian Hormone, Assisted Reproductive Technology, Ovarian Reserve

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