In the case of a medical emergency such as an out of-hospital cardiac arrest, the chances of a person's survival decrease rapidly if they are not attended to immediately. Modern hospitals well equipped to deal with such a situation however, an ambulance may get stuck in traffic and it may take responders time to reach locations deep within a building. Each year between 180,000 and 400,000 people die due to cardiac arrest. However, it is possible to reduce this number. Unmanned Aerial Vehicles (UAV) has regularly been used for remote sensing and aerial imagery collection, but the technology exists to allow the use of drones to respond to medical emergencies. To ensure that drones can reach the victim and provide medical aid, a framework for reacting to emergency circumstances, is required. This paper proposes a system-of systems-based framework that is capable of responding to one of the most acute medical emergencies, a heart attack. The proposed architecture consists that work in coordination to ensure that the drone can achieve safe flight and provide medical aid. An autonomous command and control system is discussed. This system also allows manual control from a remote location.