Abstract. The content of lead in muscles, liver, spleen and testicles is studied in Hereford bulls, aged 18 months. Selectivity of Pb accumulation is identified in organs and tissues. Pb level in organs and tissues may be ranged as follows: liver>spleen>muscles>testicles in the ratio 4.7: 4.4: 1.2: 1. It is shown that the increased concentration of lead in testicles decreases the content of vitamins. Some biological indexes of blood serum are indicators of Pb level in muscles and liver.