Inflammatory linear verrucous epidermal nevus (ILVEN) is a rather uncommon dermatosis that typically has an early age of onset, is unilateral, localized, pruritic and relatively refractory to treatment. Atypical presentations of ILVEN have also been described and include late onset in life, widespread involvement and response to treatment. We report the adult onset of an extremely pruritic systemized eruption in both mother and her daughter that clinically and histologically was most compatible with ILVEN. The eruptions were also partially responsive to therapy.

Welsh mining community, and from a study of the comparative mortality from lung cancer in Welsh mining and non-mining towns. These results, together with previously published data which have been reviewed, show that in Great Britain the death rate of coal-miners from cancer of the lung is appreciably lower than the national rate for men of comparable age.This occupational trend is not explicable by any of the factors which are known to influence the prevalence of the disease in the general population. In particular there is much evidence that the cigarette consumption of miners at least equals that of men in other occupations. The exclusion of this and other recognized aetiological factors suggests that the reduced mortality of miners from this disease is a specific effect of their occupation.This effect might be a consequence of the inhalation of coal-dust, for there is some evidence that the incidence of death from lung cancer is lowest among miners whose exposure to coal-dust has been greatest.The recorded mortality from cancer of the lung is appreciably lower for coal-miners than for other men of similar age. The purpose of this paper is to review the data on which this statement is based, to present supporting evidence from previously unpublished material, and to seek aetiological factors which might explain this occupational trend. Kennaway and Kennaway (1936) (Kennaway and Kennaway, 1947).Corroboratory data are contained in the Registrar General's Decennial Supplement on Occupational Mortality (1958), in which it is stated that in England and Wales in 1949-53 the standardized mortality ratio (S.M.R.) of mineworkers and quarrymen aged 20 to 65 for cancer of the lung was 71. For the same period in Scotland the corresponding S.M.R. for coal-miners aged 15 to 64 was 80 (Registrar General for Scotland, 1956). These low ratios were not recorded for most other types of cancer, and during the same five-year period the Registrar General found the S.M.R. for cancer at all sites in the body to be almost the same in miners (S.M.R. = 95) as the national average for men; the low ratio for lung cancer contrasted with a high ratio (S.M.R. = 149) for cancer of the stomach.Evidence concerning the frequency of lung cancer among coal-miners was acquired by Doll (1958)

The differences in microscopic appearance which characterize the main histological types of lung cancer suggest associated differences in biological behaviour. For example, their growth rates might be expected to increase as the degree of cell differentiation decreases, in which case the least differentiated tumours would be the most malignant.One method of assessing the relative behaviour of different types of tumour is by studying the survival rates of untreated patients in whom they occur. However, among untreated patients with lung cancer the course of the disease is so short that survival differences between the histological types are small. A more useful index of relative biological behaviour is provided by comparative survival rates after treatment. Many papers have been written about this, mainly on the relation between tumour histology and survival after surgery, and these have been reviewed by Bignall (1958). From the data included in this review, and from other more recent publications, several apparent associations emerge.

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